Multimorbidity and Patient Safety Incidents in Primary Care: A Systematic Review and Meta-Analysis

PloS One
Maria PanagiotiPeter Bower

Abstract

Multimorbidity is increasingly prevalent and represents a major challenge in primary care. Patients with multimorbidity are potentially more likely to experience safety incidents due to the complexity of their needs and frequency of their interactions with health services. However, rigorous syntheses of the link between patient safety incidents and multimorbidity are not available. This review examined the relationship between multimorbidity and patient safety incidents in primary care. We followed our published protocol (PROSPERO registration number: CRD42014007434). Medline, Embase and CINAHL were searched up to May 2015. Study design and quality were assessed. Odds ratios (OR) and 95% confidence intervals (95% CIs) were calculated for the associations between multimorbidity and two categories of patient safety outcomes: 'active patient safety incidents' (such as adverse drug events and medical complications) and 'precursors of safety incidents' (such as prescription errors, medication non-adherence, poor quality of care and diagnostic errors). Meta-analyses using random effects models were undertaken. Eighty six relevant comparisons from 75 studies were included in the analysis. Meta-analysis demonstrated that physical-menta...Continue Reading

References

Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
May 26, 2001·Diabetes Care·R J AndersonP J Lustman
Nov 7, 2002·Archives of Internal Medicine·Jennifer L WolffGerard Anderson
Aug 22, 2003·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Clare McGuiness, Beverly Sibthorpe
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Jul 24, 2004·Journal of the American Geriatrics Society·Terry S FieldDavid W Bates
Oct 13, 2004·Archives of Internal Medicine·Philip D SloaneJ Richard Hebel
Nov 30, 2004·Statistics in Medicine·David J Spiegelhalter
Apr 9, 2005·Journal of the American Geriatrics Society·Pieter T M van DijkMiel W Ribbe
Apr 15, 2005·Healthcare Quarterly·Judith Dyke
May 21, 2005·The American Journal of Geriatric Pharmacotherapy·Sally K RiglerMarty Eng
Jun 2, 2005·Annals of Family Medicine·Martin FortinLise Lapointe
Jul 12, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marco A LimaIgor J Koralnik
Aug 5, 2005·Journal of the American Geriatrics Society·Mary Jo V PughDan R Berlowitz
Aug 11, 2005·JAMA : the Journal of the American Medical Association·Cynthia M BoydAlbert W Wu
Aug 25, 2005·Psychological Medicine·Jasper NuyenGeertrudis A M Van den Bos
Oct 15, 2005·Medical Care·Michael L ParchmanShuko Lee
Dec 6, 2005·Neurosurgery Clinics of North America·Vincent C Traynelis
Dec 13, 2005·Psychiatric Services : a Journal of the American Psychiatric Association·Isabel T LagomasinoKenneth B Wells
Jan 10, 2006·Journal of the American Geriatrics Society·Jeffrey S HarmanHenrique Kallas
Mar 30, 2006·Annals of Family Medicine·Barbara Starfield
Jul 4, 2006·Psychiatric Services : a Journal of the American Psychiatric Association·Sarah L KreinMarcia Valenstein
Sep 27, 2006·Archives of Internal Medicine·P Michael HoDavid J Magid
Mar 14, 2007·Research in Social & Administrative Pharmacy : RSAP·Sherrilene ClassenNabih Asal
Apr 7, 2007·Psychiatric Services : a Journal of the American Psychiatric Association·Richard W GoldbergLisa B Dixon
May 29, 2007·Epilepsy & Behavior : E&B·Seth A MensahMike P Kerr
Jun 15, 2007·The New England Journal of Medicine·Takahiro HigashiPaul G Shekelle
Dec 6, 2007·Journal of General Internal Medicine·Christine VogeliDavid Blumenthal
Dec 12, 2007·Clinical Cardiology·Ana RuigómezNils Edvardsson
Mar 6, 2008·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·David ReevesAnne Rogers
Apr 23, 2008·Journal of General Internal Medicine·Constance H FungElizabeth A McGlynn
Jun 21, 2008·BMJ : British Medical Journal·John P A IoannidisHannah R Rothstein
Sep 6, 2008·Journal of the American Geriatrics Society·Terri R FriedMary E Tinetti
Sep 24, 2008·Journal of General Internal Medicine·SeungJin Bae, Meredith B Rosenthal
Oct 28, 2008·Social Science & Medicine·Don Nutbeam

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Citations

Feb 27, 2017·International Journal of Clinical Pharmacy·Susana Sánchez-FidalgoBernardo Santos-Ramos
Jan 13, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Maria PanagiotiPeter Bower
Nov 21, 2017·BMC Health Services Research·Michaela L SchiøtzAnne Frølich
Jul 2, 2020·Medicina·Emilia BłeszyńskaMarcin Renke
May 24, 2019·Medical Care Research and Review : MCRR·Morgan C ShieldsBarbra Rabson
Feb 14, 2020·International Journal for Equity in Health·Sudeh Cheraghi-SohiCaroline Sanders
Jul 17, 2019·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Kathryn NicholsonAmardeep Thind
Oct 1, 2020·International Journal of Clinical Pharmacy·Nuria García-Agua SolerFrancisco Jódar-Sánchez
Oct 8, 2019·Annual Review of Pharmacology and Toxicology·Alpana MairTobias Dreischulte
Oct 22, 2020·The American Journal of Hospice & Palliative Care·Cara L McDermottJ Randall Curtis
Dec 12, 2020·PloS One·Shamini PrathapanBatheegama Gamarachchige Gayasha Kavindi Somathilake
Mar 18, 2021·Journal of the American Geriatrics Society·Kathryn NicholsonParminder Raina
May 10, 2021·Lancet·Michael AndersonAlistair McGuire
Jul 12, 2021·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Leila PaukkonenHelvi Kyngäs
Sep 23, 2021·International Journal of Clinical Practice·Ami Schattner
Aug 4, 2017··Jimeng SunWalter F. Stewart

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Software Mentioned

Excel
Comprehensive Meta - analysis ( CMA )
metabias
STATA
Cinahl

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