Multiobjective optimization of tibial locking screw design using a genetic algorithm: Evaluation of mechanical performance

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Ching-Chi HsuJinn Lin

Abstract

Breakage or loosening of locking screws may impair fracture fixation or bone healing in locked nailing of tibial fractures. Bending strength and bone holding power, two important design objectives of locking screws, may conflict with each other. The present study used multiobjective optimization with a genetic algorithm to investigate the optimal designs with respect to these two objectives. Three-dimensional finite element models for analyzing bending strength and bone holding power of locking screws were created first. Through use of a Taguchi L25 orthogonal array, two objective functions were developed by least-squares regression analyses. Then, the trade-off solutions between the two objectives known as Pareto optima were explored by a weighted-sum aggregating approach under geometric constraints. The objective functions, reliably reflecting the finite element results, were valid for multiobjective studies. The Pareto fronts of the screws with 4.5-mm and 5.0-mm outer diameters were similar. The "knee" region of the Pareto front, characterized by the fact that a small improvement in either objective will cause a large deterioration in the other objective, might be the favored choice of optimal designs. The commercially avail...Continue Reading

References

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Mar 5, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Ichiro TagaYasuhiro Fukui
Jul 19, 2005·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Ching-Chi HsuJinn Lin

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Citations

Sep 8, 2010·Journal of Biomechanical Engineering·Ching-Kong ChaoChing-Chi Hsu
Apr 17, 2009·Dental Materials : Official Publication of the Academy of Dental Materials·Chun-Li LinYi-Feng Lin
Jul 6, 2012·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Cornelia Katharina MuellerStefan Schultze-Mosgau
Jan 22, 2013·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Ching-Chi Hsu

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