PMID: 2488252Jan 1, 1989Paper

Multiparameter analysis approach of antiparasitic structure-activity relationships in function of the parasite taxonomy

Annales pharmaceutiques françaises
J LacroixR Lacroix

Abstract

In this paper the authors have studied the structure-parasitic activity relationships through the Chemical Abstracts data base which groups together the works published in this field for the last twenty years. With mathematical methods of multidimensional data reduction using a computer it has been possible to validate the classification of human parasites on the base of their sensitivity to chemical families. The specificity of the pharmacochemical relationships was described through two factorial maps. This work shows that it is possible to find new chemical series with potential parasitic activity.

Related Concepts

Related Feeds

Antiparasitics

Antiparasitics are medications which are indicated for the treatment of parasitic diseases. Discover the latest research on antiparasitics here.

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Related Papers

Journal of Enzyme Inhibition and Medicinal Chemistry
Alia Michaelidou, D Hadjipavlou-Litina
The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy
Z PangS He
© 2022 Meta ULC. All rights reserved