Multiparametric MR Imaging with High-Resolution Dynamic Contrast-enhanced and Diffusion-weighted Imaging at 7 T Improves the Assessment of Breast Tumors: A Feasibility Study

Radiology
K PinkerT H Helbich

Abstract

To ascertain whether multiparametric magnetic resonance (MR) imaging of the breast in combination with dynamic contrast material-enhanced (DCE) imaging and diffusion-weighted imaging (DWI) at 7 T is feasible and improves diagnostic accuracy. From December 2011 to December 2013, 40 patients with suspicious breast lesions were included in this institutional review board-approved prospective study. Before bilateral multiparametric MR imaging of the breast at 7 T, all patients gave written informed consent. Lesions were classified according to Breast Imaging Reporting and Data System (BI-RADS) and assessed for apparent diffusion coefficient (ADC) values by two readers independently. For combined analysis of DCE MR imaging and DWI, the BI-RADS-adapted reading algorithm, which adapted ADC thresholds to the BI-RADS assessment category, was used. Diagnostic values of multiparametric, DCE MR imaging, and DWI were calculated. Receiver operating characteristic curve analysis was performed. Image quality and interreader agreement were assessed. Histopathologic results were used as the highest standard. There were 29 malignant and 17 benign lesions (range, 6-95 mm; mean, 23.3 mm). Multiparametric MR imaging yielded a sensitivity of 100% (29...Continue Reading

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Citations

Nov 29, 2015·Magnetic Resonance Imaging Clinics of North America·Habib Rahbar, Savannah C Partridge
Jul 13, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ileana HancuEk T Tan
Jul 22, 2016·Journal of Magnetic Resonance Imaging : JMRI·Jose R TeruelEric E Sigmund
Oct 1, 2016·Journal of Magnetic Resonance Imaging : JMRI·Savannah C PartridgeEric E Sigmund
Apr 4, 2017·Journal of Magnetic Resonance Imaging : JMRI·Oliver Kraff, Harald H Quick
Sep 15, 2019·Journal of Magnetic Resonance Imaging : JMRI·Mami IimaKaori Togashi
Jun 24, 2017·Journal of Magnetic Resonance Imaging : JMRI·Maria Adele MarinoKatja Pinker-Domenig
Sep 13, 2021·Investigative Radiology·Tanja PlattDaniel Paech

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