Multiphasic disseminated encephalomyelitis, systemic lupus erythematosus and antiphospholipid syndrome

Clinical Neurology and Neurosurgery
Laura OrdonezVictor M Rivera

Abstract

We report a case of multiphasic disseminated encephalomyelitis (MDEM) associated with systemic lupus erythematosus (SLE) and antiphospholipid syndrome. The initial presentation was suggestive of multiple sclerosis. Further clinical attacks, MRI imaging, and CSF findings led to a diagnosis of disseminated encephalomyelitis (DEM). Multiple episodes of neurological dysfunction, which differed in clinical presentation, further categorized the diagnosis as multiphasic DEM. The co-occurrence SLE and antiphospholipid syndrome is unusual and provided an additional diagnostic challenge.

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Citations

Apr 22, 2008·Journal of Neurology·Pedro Emilio BermejoCarlos Escamilla
Apr 8, 2014·Neurología : publicación oficial de la Sociedad Española de Neurología·M C Gil AlzuetaM T Cabada Giadás
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Aug 23, 2012·Neurological Research·Saeed Talebzadeh NickAlireza Minagar
Dec 27, 2007·Yonsei Medical Journal·Penka A Atanassova
Jun 3, 2016·Critical Care Nurse·Wei-Ti ChenKon-Ping Lin

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