PMID: 8990706Nov 1, 1996Paper

Multiple basaloid cell hamartoma with alopecia and autoimmune disease (systemic lupus erythematosus)

The Journal of Dermatology
T AkasakaM C Mihm

Abstract

We report a 22-year-old Japanese woman with multiple basaloid cell hamartoma with alopecia and autoimmune disease (systemic lupus erythematosus). She presented with infiltrated large annular, brown-violet, erythematous plaques with atrophic areas in the center on her right cheek, left abdomen and left knee. She also had progressive multiple follicular keratotic papules on her scalp, face, neck, and both axilla and hair loss from her scalp, eyebrow, and axilla. Serologically, rheumatoid factor (+ + +), rheumatoid arthritis hemagglutination test (x1280), and anti-nuclear antigen (x160) were positive. Histological findings of the annular lesion showed liquefaction degeneration of basal cells, lymphocytic infiltration around hair follicles and capillaries, and panniculitis with lymphoid cell infiltration, which was diagnosed as lupus erythematosus profundus. The histological findings of multiple follicular papular lesions of the scalp and neck showed aggregations of basaloid cells, partially with hair-bulb-like structures, which was diagnosed as trichoepithelioma. Taken together, the histogenesis of multiple basaloid cell hamartoma is thought to share the same basis with autoimmune disease.

References

Aug 1, 1992·Journal of the American Academy of Dermatology·M H Brownstein
Aug 1, 1988·Journal of the American Academy of Dermatology·S MiyakawaM Sugawara
Feb 1, 1985·Journal of Cutaneous Pathology·A H Mehregan, S Baker
Aug 1, 1993·Journal of Cutaneous Pathology·E Alessi, A Azzolini

❮ Previous
Next ❯

Citations

Oct 20, 2004·The Journal of Dermatology·Kenta TsuruMasato Ueda
May 28, 2010·Journal of Cutaneous Pathology·Alireza SepehrSteven R Tahan
May 15, 2010·International Journal of Dermatology·Xi-chuan YangBai-yu Zhong
Sep 24, 2005·Clinics in Dermatology·Uwe Wollina, Gert Hein
Nov 9, 2000·The British Journal of Dermatology·H ShimizuM Ueda
Jul 18, 2002·The Australasian Journal of Dermatology·Steven Kossard
Jan 12, 2007·Journal of Cutaneous Pathology·L L BraileyS M Ruhoy
Sep 1, 2007·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Aradhna SaxenaJ Ramsey Mellette
Mar 26, 2003·The American Journal of Dermatopathology·Debra M JihJohn T Seykora
Mar 31, 2012·Ophthalmic Plastic and Reconstructive Surgery·Frederick A JakobiecNancy Kim
Jun 28, 2018·American Journal of Clinical Dermatology·Siriorn UdompanichPoonkiat Suchonwanit
Aug 18, 2020·American Journal of Ophthalmology Case Reports·Nicole JedrzynskiMichael Kazim
Jan 30, 2019·Annales de dermatologie et de vénéréologie·G HazemannB Cribier
Jun 17, 2021·The American Journal of Dermatopathology·Ijeuru ChikekaViktoryia Kazlouskaya

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.