Multiple Cancers of the Biliary Tract and Pancreatic Duct after Cholecystectomy for Gallbladder Cancer in a Patient with Pancreaticobiliary Maljunction

Internal Medicine
Kazuya KoizumiYutaka Kohgo

Abstract

We herein report the rare case of a 76-year-old woman who underwent cholecystectomy with bile duct resection for advanced gallbladder cancer associated with pancreaticobiliary maljunction (PBM) and subsequently developed multiple cancers of the pancreaticobiliary system (the distal bile duct, intrahepatic duct and pancreatic duct) after the operation. We performed conventional endoscopic retrograde cholangiopancreatography (ERCP) using a side-viewing scope to evaluate the masses in the distal bile duct and the pancreatic duct. We also performed ERCP using double-balloon enteroscopy (DBE) to observe the mass in the intrahepatic duct. It was possible to directly observe the lesion using DBE and to perform a biopsy under visual control. All lesions were correctly diagnosed by the combination of ERCP using different endoscopes. The present case suggests that it is necessary to pay close attention (with regard to carcinogenesis) to the whole pancreaticobiliary system in patients with PBM. In addition, the combination of ERCP using DBE and a side-viewing scope may be useful for making a precise diagnosis in patients with altered biliary anatomy who have multiple cancers of the pancreaticobiliary system.

References

Mar 1, 1980·Acta Pathologica Japonica·K SudaK Hashimoto
Nov 5, 2003·Journal of Hepato-biliary-pancreatic Surgery·Seiki TashiroUNKNOWN Committee for Registration of the Japanese Study Group on Pancreaticobiliary Maljunction
Nov 30, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Hidenori HarutaHideo Kawarasaki
May 27, 2008·Langenbeck's Archives of Surgery·Takahiko FunabikiShin Ishihara
Jun 7, 2008·Journal of Hepato-biliary-pancreatic Surgery·Yukiko MinamiToshimasa Tsujinaka
Dec 5, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Terumi KamisawaTsuneo Sasaki
Dec 17, 2010·World Journal of Gastrointestinal Surgery·Ahlem LahmarSabah Mzabi-Regaya
Dec 24, 2010·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yoshinobu OkabeMichio Sata
Aug 2, 2012·World Journal of Gastroenterology : WJG·Tatsuya KoshitaniToshikazu Yoshikawa
Oct 20, 2012·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Hisashi HatanakaKentaro Sugano
Oct 24, 2014·World Journal of Gastroenterology : WJG·Narongsak Rungsakulkij, Paisarn Boonsakan

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