Multiple differences between patients who initiate fish oil supplementation post-myocardial infarction and those who do not: the TRIUMPH Study

Nutrition Research
William S HarrisJohn A Spertus

Abstract

The utility of fish oil supplements (FOS) in patients who survive an acute myocardial infarction (MI) remains controversial, with randomized trials showing less benefit than observational studies would suggest. The differences in the characteristics of MI patients who use FOS in routine clinical care are unknown but may help explain this discrepancy. We used data from a 24-site registry study in which extensive information was available on 4340 MI patients at admission and 1, 6, and 12 months postdischarge. After excluding those using FOS at admission (n = 651), those who died before the 1-month follow-up visit (n = 63), and those with missing data at 1 month (n = 1228), 2398 remained. Of them, 377 (16%) started FOS within 1 month of their MI. We analyzed 53 patient characteristics associated with FOS use. We observed differences (P < .001) in 20 demographic, socioeconomic, treatment, disease severity, and health status domains. The FOS users were more likely than nonusers to be white, married, financially secure, highly educated, and eating fish. They also had a higher ejection fraction at discharge, were more likely to have had in-hospital percutaneous coronary interventions, and were more likely to have participated in cardi...Continue Reading

References

Oct 2, 1986·The New England Journal of Medicine·B H WeinerM H Johnson
Apr 18, 2003·European Journal of Clinical Nutrition·F BarziUNKNOWN GISSI-Prevenzione Investigators
Jun 10, 2004·JAMA : the Journal of the American Medical Association·Kim A EagleUNKNOWN GRACE Investigators
Jun 23, 2004·Preventive Medicine·William S Harris, Clemens Von Schacky
Jul 20, 2010·Lancet·Palaniappan SaravananPhilip C Calder
Dec 1, 2010·BMJ : British Medical Journal·Pilar GalanUNKNOWN SU.FOL.OM3 Collaborative Group
Mar 29, 2011·The Annals of Thoracic Surgery·Umberto BenedettoRiccardo Sinatra
Jun 24, 2011·The New England Journal of Medicine·Raffaele De Caterina
Jul 2, 2011·Mayo Clinic Proceedings·Adam C SalisburyJohn A Spertus
Jul 21, 2011·Circulation. Cardiovascular Quality and Outcomes·Suzanne V ArnoldUNKNOWN Cardiovascular Outcomes Research Consortium
Dec 22, 2011·Current Opinion in Clinical Nutrition and Metabolic Care·Richard J Deckelbaum, Philip C Calder
Sep 13, 2012·JAMA : the Journal of the American Medical Association·Evangelos C RizosMoses S Elisaf
Dec 1, 2012·Current Opinion in Clinical Nutrition and Metabolic Care·William S Harris
Feb 6, 2014·American Journal of Epidemiology·Griffith A BellEmily White
May 31, 2014·Journal of Lipid Research·Chuanming LuoHuanxing Su
Jun 17, 2014·The British Journal of Nutrition·Michael J JamesLeslie G Cleland

❮ Previous
Next ❯

Citations

Sep 18, 2016·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Jenifer I FentonWilliam S Harris
Oct 11, 2016·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Rahul ChaudharyPaul A Gurbel
Mar 7, 2019·The Proceedings of the Nutrition Society·William S Harris, Francis B Zotor

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved