Multiple endocrine neoplasia-2B presenting with orthodontic relapse

The Angle Orthodontist
Brent AccursoCarl M Allen

Abstract

The multiple endocrine neoplasia (MEN) syndromes are a relatively uncommon group of genetic disorders characterized by the development of tumors in various endocrine organs. MEN type 2B is of particular interest to the dental profession because of its oral manifestations, which are often some of the earliest clinically detectable signs of the disorder. Early identification of this syndrome is critical because affected patients often develop a characteristic malignancy, medullary carcinoma of the thyroid, at a very early age. We describe a 17-year-old male whose initial diagnosis of MEN-2B was triggered by his orthodontist's request for an oral and maxillofacial pathology consultation to evaluate the patient's oral abnormalities.

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Citations

Dec 3, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Robert Bruce MacIntoshMichael Lee
Nov 22, 2011·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Yu UsamiSatoru Toyosawa
Jul 10, 2019·Imaging Science in Dentistry·Hamed MortazaviFatemeh Safari
Jun 23, 2018·Head and Neck Pathology·Faraj M AlotaibyIndraneel Bhattacharyya

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