Multiple fiber laser-induced thermotherapy for ablation of large intrahepatic tumors

Photomedicine and Laser Surgery
Liesbeth M VeenendaalRichard van Hillegersberg

Abstract

The aim of this study was to test three techniques used simultaneously to increase lesion size. Laser-induced thermotherapy (LITT) is a method of local tumor ablation, which may prolong survival in patients with unresectable liver metastases. The main limitation has been the production of lesions with sufficient tumor-free margin. LITT treatment was performed with water-cooled, multiple fiber application and hepatic blood flow occlusion in six patients with unresectable intrahepatic metastases. Response was measured by computed tomography scan. In all patients, tumors were effectively ablated. In two patients with colorectal metastases, lesions up to 8.6 cm could be created. The use of watercooled multiple fiber application and hepatic inflow occlusion makes LITT an effective ablative method, expanding the treatment options for patients with large intrahepatic masses.

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Citations

Oct 31, 2006·Photomedicine and Laser Surgery
Dec 23, 2011·Radiology Research and Practice·Claudio Maurizio PacellaGiovanni Giuseppe Di Costanzo
Jun 28, 2006·World Journal of Surgical Oncology·Liesbeth M VeenendaalRichard van Hillegersberg
Jan 29, 2011·Radiology·Muneeb AhmedS Nahum Goldberg
Nov 19, 2013·Techniques in Vascular and Interventional Radiology·Erica M Knavel, Christopher L Brace
Dec 7, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J Evans
Oct 29, 2014·World Journal of Hepatology·Giovan Giuseppe Di CostanzoClaudio Maurizio Pacella
Jun 14, 2013·Acta Radiologica·Giovan Giuseppe Di CostanzoClaudio Maurizio Pacella
Jul 9, 2008·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Pretesh R PatelVictor Frenkel

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