PMID: 6170479Jun 1, 1981

Multiple forms of bovine kidney alkaline phosphatase

Clinical Biochemistry
K CavanaghH F Fackrell

Abstract

Partial purification of bovine kidney alkaline phosphatase produced two fractions (F1, F2). Double immunodiffusion experiments using antiserum against the pooled kidney fractions showed a complete fusion of the precipitin line of bovine kidney F2 with those of bovine kidney F1, liver, bone, and placental alkaline phosphatases. No reaction was observed between the antiserum and alkaline phosphatase from either bovine intestine or human kidney. Crossed immunoelectrophoresis of fraction F2 produced two peaks that crossed each other and stained for enzyme activity. This finding is discussed in light of recent reports of multiple antigenic forms of alkaline phosphatase form human and rabbit kidney.

References

Jan 1, 1977·International Archives of Allergy and Applied Immunology·L Korngold
Aug 22, 1975·Annals of the New York Academy of Sciences·H SuzukiK Miki
Jan 16, 1978·Clinica Chimica Acta; International Journal of Clinical Chemistry·R OtaniY Yamamura
Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·G Moak, H Harris
Mar 1, 1976·Hoppe-Seyler's Zeitschrift für physiologische Chemie·M Khattab, G Pfleiderer
Jul 1, 1977·Annals of Clinical Biochemistry·J S Abdullah, E Gowland
Jan 1, 1976·International Archives of Allergy and Applied Immunology·L Korngold
Jan 1, 1972·International Archives of Allergy and Applied Immunology·A M PankovichJ Stevens
Jan 1, 1970·International Archives of Allergy and Applied Immunology·L Korngold
May 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·D J GoldsteinH Harris

Related Concepts

Alkaline Phosphatase
Antigenic Specificity
Skeletal Bone
Bos indicus
Immunodiffusion Measurement
Immunoelectrophoresis, Two-Dimensional
Alloenzymes
Kidney
Liver
Placenta

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