Multiple genes encoding the conserved CCAAT-box transcription factor complex are expressed in Arabidopsis

Plant Physiology
D EdwardsA G Smith

Abstract

The CCAAT motif is found in the promoters of many eukaryotic genes. In yeast a single complex of three proteins, termed HAP2, HAP3, and HAP5, binds to this sequence, and in mammals the three components of the equivalent complex (called variously NF-Y, CBF, or CP1) are also represented by single genes. Here we report the presence of multiple genes for each of the components of the CCAAT-binding complex, HAP2, 3,5, from Arabidopsis. Three independent Arabidopsis HAP subunit 2 (AtHAP2) cDNAs were cloned by functional complementation of a yeast hap2 mutant, and two independent forms each of AtHAP3 and AtHAP5 cDNAs were detected in the expressed sequence tag database. Additional homologs (two of AtHAP3 and one of AtHAP5) have been identified from available Arabidopsis genomic sequences. Northern-blot analysis indicated ubiquitous expression for each AtHAP2 and AtHAP5 cDNA in a range of tissues, whereas expression of each AtHAP3 cDNA was under developmental and/or environmental regulation. The unexpected presence of multiple forms of each HAP homolog in Arabidopsis, compared with the single genes in yeast and vertebrates, suggests that the HAP2,3,5 complex may play diverse roles in gene transcription in higher plants.

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Citations

May 16, 2007·Molecular Genetics and Genomics : MGG·Melissa J Roach, Michael K Deyholos
Jan 15, 2008·Molecular Genetics and Genomics : MGG·Thiruvengadam ThirumuruganNori Kurata
Jul 1, 2011·The Journal of Microbiology·Wenbing Yin, Nancy P Keller
Mar 31, 2004·Plant Physiology and Biochemistry : PPB·Katsumi YazawaHiroshi Kamada
Dec 8, 2009·Nucleic Acids Research·Marcel ThönAxel A Brakhage
Aug 15, 2008·Plant & Cell Physiology·Jérôme Verdier, Richard D Thompson
Jan 2, 2003·The Plant Cell·Raymond W KwongJohn J Harada
Jan 1, 2013·The Plant Cell·Katia PetroniRoberto Mantovani
Nov 10, 2005·Eukaryotic Cell·David S McNabb, Inés Pinto
May 1, 2008·Annual Review of Plant Biology·Franziska TurckGeorge Coupland
Feb 2, 2011·The Journal of General and Applied Microbiology·Yuichi NakajimaTakashi Kamakura
Feb 15, 2013·Genetics and Molecular Research : GMR·F XuS Y Cheng
Mar 14, 2014·Journal of Experimental Botany·Andrei Smertenko, Peter V Bozhkov
Feb 13, 2003·Proceedings of the National Academy of Sciences of the United States of America·Hyeseung LeeJohn J Harada
Oct 10, 2007·Proceedings of the National Academy of Sciences of the United States of America·Donald E NelsonJacqueline E Heard

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