Multiple herpetic whitlow lesions in a patient with chronic lymphocytic leukemia

American Journal of Hematology
Edward SmithAmy McMichael

Abstract

Herpetic whitlow, a herpes simplex virus infection involving the digits, most commonly presents as a vesicular eruption involving a single digit. Diagnosis of herpetic whitlow can usually be made with the history of exposure, the characteristic vesicular eruption, and a positive Tzank smear and/or viral culture. We describe a case of herpetic whitlow in a patient finishing 6 cycles of chemotherapy for refractory chronic lymphocytic leukemia that presented with a bilateral, multi-digit, crusted eruption of the hands. This is an illustrative case of an immunocompromised host status altering appearance and course of cutaneous disease such that the history and physical exam alone may not help in diagnosing atypical presentations of herpetic infections. This case underscores the necessity for clinico-histopathologic correlation.

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Citations

Dec 22, 2009·Future Microbiology·Gargi DasguptaLbachir BenMohamed
Nov 9, 2010·Journal of the American Academy of Dermatology·Odile WautersArjen F Nikkels
Nov 22, 2008·Journal of the American Academy of Dermatology·Pooja KheraJoseph C English
Jun 11, 2010·International Journal of Dermatology·Omar A IbrahimiAbrar Qureshi
Feb 7, 2019·Anais Brasileiros De Dermatologia·Clívia Maria Moraes de Oliveira CarneiroFernanda Cecilia de Oliveira Costa Ataide Brito
Jan 1, 2019·Anais Brasileiros De Dermatologia·Clívia Maria Moraes de Oliveira Carneirode Oliveira Costa Ataide Brito Fernanda Cecilia
Mar 3, 2021·International Journal of Dermatology·Suparna DasRam Chander

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