Multiple infection of porcine Torque teno virus in a single pig and characterization of the full-length genomic sequences of four U.S. prototype PTTV strains: implication for genotyping of PTTV

Virology
Y W HuangX J Meng

Abstract

Porcine Torque teno virus (PTTV) was recently shown to partially contribute to the experimental induction of porcine dermatitis and nephropathy syndrome and postweaning multisystemic wasting syndrome in pigs in the United States. We report here the identification of four distinct full-length genomic sequences of PTTV strains from a single pig in Virginia. Detailed analyses of the genomic organization, the degree of variability and the characteristics of conserved nucleotide and amino acid motifs of PTTV were conducted. The results showed that these four prototype U.S. strains of PTTV identified from the same pig represent distinct genotypes or subtypes and a revised classification system for PPTV is subsequently proposed. This is the first study documenting multiple PTTV infections with distinct genotypes or subtypes in a single pig. The identification of novel PTTV strains from pigs in the United States also pave the way for future disease characterization and genotyping of PTTV.

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Citations

Apr 1, 2014·International Journal of Food Microbiology·Danielle LeblancJulie Brassard
Jan 15, 2014·Gene·Huiqiang WenLingxia Han
Nov 5, 2011·Virology Journal·Zhiwei WuYingshun Zhou
Jan 4, 2013·Veterinary Research Communications·Raquel de Arruda LemeAmauri Alcindo Alfieri
Jan 10, 2012·Veterinary Microbiology·Lavanya RammohanSheela Ramamoorthy
Jun 18, 2010·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·C X ZhuX G Hua
Mar 19, 2014·Veterinary Microbiology·Huiqiang WenHongyan Chen
Jan 19, 2012·Transboundary and Emerging Diseases·T Kekarainen, J Segalés
Sep 8, 2012·The Journal of General Virology·Vivian Cornelissen-KeijsersTuija Kekarainen
Jul 1, 2011·The Journal of General Virology·Laura Martínez-GuinóTuija Kekarainen
Jun 9, 2015·Vaccine·Alexandra Jiménez-MelsióTuija Kekarainen
Jun 8, 2011·Virus Research·Daoliang LanZhibiao Yang
Nov 30, 2010·Veterinary Microbiology·Martí CorteyJoaquim Segalés
Oct 5, 2013·Virus Research·Alexandra Jiménez-MelsióTuija Kekarainen
Apr 12, 2012·Journal of Virology·Yao-Wei HuangXiang-Jin Meng
Jan 10, 2012·Transboundary and Emerging Diseases·X J Meng
Apr 16, 2011·The Veterinary Record·X LiuH Yang
Jan 3, 2021·Research in Veterinary Science·Nariman ShahhosseiniGary Wong
May 15, 2020·Virus Research·Brett WebbSheela Ramamoorthy
Feb 11, 2018·Veterinary Microbiology·Gagandeep Singh, Sheela Ramamoorthy
May 3, 2011·Research in Veterinary Science·Giseli A RitterbuschJanice R Ciacci-Zanella
Aug 8, 2021·Virology·Simona KrabergerArvind Varsani

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