Multiple joint involvement in total knee replacement for osteoarthritis: Effects on patient-reported outcomes

Arthritis Care & Research
A V PerruccioA M Davis

Abstract

To determine whether symptomatic (painful/problematic) joints pre-total knee replacement (TKR) surgery influence 1) pre- and 12-month post-TKR patient-reported outcomes (pain, physical function, and mood [fatigue, anxiety, and depression]) and 2) postsurgical pain and function mediated through mood. A total of 494 participants completed the patient-reported outcome measures pre- and 12-months post-TKR. Symptomatic (painful/problematic) joints affected by arthritis were indicated on a homunculus presurgery. Covariate data included age, sex, educational attainment, body mass index, and comorbidity. Pre- and postsurgical outcome scores were regressed on symptomatic joint sites and covariates using linear regression analyses; postsurgical scores additionally were regressed on presurgery scores. Path analyses examined whether the effects of symptomatic joint sites on postsurgical pain and function were mediated through mood. The age range was 35-88 years (mean 65 years) and 65% were women. Forty-six percent reported ≥4 symptomatic joints (other than the surgical knee). Pre- and postsurgery, worse outcome scores were observed with increasing joint count. Adjusted for covariates, individuals reporting symptomatic ankles/feet/toes, nec...Continue Reading

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Citations

Aug 14, 2013·BMC Musculoskeletal Disorders·Liseth SiemonsThomas J Hoogeboom
Mar 19, 2013·BMC Musculoskeletal Disorders·Anthony V PerruccioUNKNOWN Arthritis Program, University Health Network
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