Multiple keratoacanthomas arising post-UVB therapy

Journal of Cutaneous Medicine and Surgery
Kenneth J CraddockVictor A Tron

Abstract

Ultraviolet (UV) radiation is known to be an important etiologic agent in the development of skin cancer. Keratoacanthoma is an unusual, well-described cutaneous neoplasm that resembles squamous cell carcinoma but spontaneously resolves. Rarely, multiple keratoacanthomas may develop. We present a case of multiple keratoacanthomas in a patient with psoriasis who had received UVB phototherapy. These lesions were hyperkeratotic papules, many of which spontaneously resolved and demonstrated the histologic characteristics of keratoacanthoma. We believe that UV radiation is the most likely etiologic factor in this patient's development of multiple keratoacanthomas. We wish to bring to the attention of clinicians this unusual adverse effect of UV treatment.

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Citations

Aug 29, 2013·Indian Dermatology Online Journal·Vineet RelhanVijay K Garg
Feb 9, 2016·Journal of the American Academy of Dermatology·Bartlomiej Kwiek, Robert A Schwartz
Aug 25, 2009·Journal of the American Academy of Dermatology·Eun Ji KwonChristine Jaworsky
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Related Concepts

Keratoacanthoma
Psoriasis
Dermatologic Disorders
Ultraviolet Therapy

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