Multiple liver metastases of pancreatic solid pseudopapillary tumor treated with resection following chemotherapy and transcatheter arterial embolization: A case report

Oncology Letters
Hidehiro TajimaTetsuo Ohta

Abstract

A 33-year-old female was diagnosed with a solid pseudopapillary tumor (SPT) of the pancreas and multiple liver metastases at the Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital (Kanazawa, Japan). Distal pancreatectomy and postoperative systemic chemotherapy with gemcitabine (GEM) and S-1, an oral fluoropyrimidine derivative, was administered, however, liver metastases became enlarged and local recurrence occurred. Therefore, the patient was referred to the Department of Gastroenterologic Surgery at the Graduate School of Medicine (Kanazawa, Japan) for hepatic arterial infusion (HAI) chemotherapy. Oral S-1 (80 mg/m(2)) was administered as well as HAI chemotherapy with GEM (1,000 mg/standard liver volume). Following 18 cycles, tumor sizes were reduced and 18-fluorodeoxyglucose positron emission tomography ((18)FDG-PET) examination revealed obvious reduction of tumor FDG uptake. Transarterial tumor embolization (TAE) was performed for the previously unresectable right subphrenic liver tumor, and the other tumors were surgically resected. The resected tumors were diagnosed as liver metastases and a local recurrence of SPT in the postoperative pathological examination, which revealed that the resecte...Continue Reading

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Citations

May 11, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Michael J WrightMatthew J Weiss
Jan 22, 2017·Digestive Diseases and Sciences·Anas GremidaDenis McCarthy
May 20, 2020·Annals of Surgical Oncology·Feng YangDeliang Fu
Aug 7, 2018·World Journal of Gastrointestinal Oncology·Li YouDe-Liang Fu
Jan 12, 2019·Journal of Pancreatic Cancer·Piyush K SharmaMartin D McCarter

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Methods Mentioned

BETA
pancreatectomy
surgical resection

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