Multiple modes of network homeostasis in visual cortical layer 2/3.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Arianna Maffei, Gina G Turrigiano

Abstract

Sensory experience is crucial for shaping the cortical microcircuit during development and is thought to modify network function through several forms of Hebbian and homeostatic plasticity. Where and when these different forms of plasticity are expressed at particular synapse types within cortical microcircuits, and how they interact, is poorly understood. Here we investigated how two different visual deprivation paradigms, lid suture (LS) and intraocular TTX, affect the local microcircuit within layer 2/3 of rat visual cortex during the classical critical period for visual system plasticity. Both forms of visual deprivation produced a compensatory increase in the spontaneous firing of layer 2/3 pyramidal neurons in acute slices derived from monocular visual cortex. TTX increased spontaneous activity through an increase in the excitation/inhibition (E/I) balance within layer 2/3. In contrast, LS decreased the E/I balance by strongly depressing excitatory transmission, and the homeostatic increase in spontaneous activity was instead achieved through an increase in the intrinsic excitability of layer 2/3 pyramidal neurons. The microcircuit in layer 2/3 can thus use different forms of homeostatic plasticity to compensate for the l...Continue Reading

References

Jan 8, 1989·The Journal of Comparative Neurology·A Burkhalter
Nov 15, 1996·Science·L C Katz, C J Shatz
Aug 17, 1999·Nature Neuroscience·N S DesaiG G Turrigiano
Feb 22, 2001·Annual Review of Physiology·G W Davis, I Bezprozvanny
Jun 25, 2002·Nature Neuroscience·Niraj S DesaiGina G Turrigiano
Jan 16, 2003·Neuron·Eve Marder, Astrid A Prinz
Feb 11, 2003·Nature Neuroscience·Cara B AllenDaniel E Feldman
Nov 5, 2003·Nature Reviews. Neuroscience·Wei Zhang, David J Linden
Jan 22, 2004·Nature Reviews. Neuroscience·Gina G Turrigiano, Sacha B Nelson
Sep 29, 2004·Neuron·Robert C Malenka, Mark F Bear
Nov 16, 2004·Nature Neuroscience·Arianna MaffeiGina G Turrigiano
Nov 24, 2004·Nature Neuroscience·Astrid A PrinzEve Marder
Feb 22, 2005·Current Opinion in Neurobiology·Marla B Feller, Massimo Scanziani
May 11, 2005·Journal of Neurobiology·Andreas Frick, Daniel Johnston
Aug 24, 2005·Proceedings of the National Academy of Sciences of the United States of America·Vardhan S DaniSacha B Nelson
Nov 2, 2005·Nature Reviews. Neuroscience·Takao K Hensch
Mar 24, 2006·The European Journal of Neuroscience·Uma R Karmarkar, Dean V Buonomano
Apr 21, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Kevin J BenderDaniel E Feldman
Jul 14, 2006·Current Opinion in Neurobiology·Sonja B HoferMark Hübener
Aug 10, 2006·Neuropharmacology·Per Jesper SjöströmSacha B Nelson
Aug 25, 2006·Nature·Arianna MaffeiGina G Turrigiano
Jan 18, 2007·Proceedings of the National Academy of Sciences of the United States of America·Robert A CrozierMark F Bear
Jun 22, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Anubhuthi Goel, Hey-Kyoung Lee
Aug 3, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Kara G Pratt, Carlos D Aizenman

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Citations

Mar 3, 2009·Nature Neuroscience·Monica L LindenMark F Bear
Oct 23, 2008·Proceedings of the National Academy of Sciences of the United States of America·Sunil P GandhiMichael P Stryker
Oct 13, 2010·Proceedings of the National Academy of Sciences of the United States of America·Megumi KanekoKevin Fox
Jan 11, 2012·Proceedings of the National Academy of Sciences of the United States of America·Adam RansonFrank Sengpiel
Aug 23, 2011·Integrative and Comparative Biology·Henner KochJan-Marino Ramirez
Nov 4, 2008·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Daniela TropeaMriganka Sur
Nov 17, 2011·Cold Spring Harbor Perspectives in Biology·Gina Turrigiano
Aug 15, 2008·Genes, Brain, and Behavior·J A HeimelC N Levelt
Apr 30, 2009·Annual Review of Neuroscience·Daniel E Feldman
Jul 11, 2008·Journal of Neurophysiology·Alfredo Fontanini, Donald B Katz
Dec 17, 2008·Journal of Neurophysiology·Katherine E Deeg
Sep 22, 2011·Developmental Neuroscience·Scott M PaluszkiewiczMolly M Huntsman
Mar 20, 2010·Neural Computation·R Rossi Pool, G Mato
Jan 26, 2012·PLoS Computational Biology·J NaudéB Delord
May 22, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Taro Toyoizumi, Kenneth D Miller
Aug 3, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Lang WangArianna Maffei
May 28, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ming GaoHey-Kyoung Lee
May 6, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Thomas E Krahe, William Guido
Jul 30, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Soroush G SadeghiKathleen E Cullen
Oct 23, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Si-yu ZhangXiao-hui Zhang
Oct 19, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Soroush G SadeghiKathleen E Cullen
Nov 9, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Nelly DaurDirk Bucher
Sep 28, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Melissa P BlackmanGina G Turrigiano
May 22, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Melanie A GaineyGina G Turrigiano
Mar 1, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Lang WangArianna Maffei
Dec 14, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Kiran Nataraj, Gina Turrigiano
May 17, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mary E Lambo, Gina G Turrigiano
Sep 3, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Henner KochJan-Marino Ramirez
Jul 5, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Wen-pei MaHuizhong Whit Tao
Aug 10, 2011·Neural Plasticity·J Alexander HeimelChristiaan N Levelt
Mar 8, 2013·Neuropharmacology·Jessica L WhittHey-Kyoung Lee
Apr 25, 2012·Neural Plasticity·Fabian C Roth, Andreas Draguhn
Jan 30, 2014·Proceedings of the National Academy of Sciences of the United States of America·Lu LiDaniel E Feldman
Jan 15, 2014·Neuropharmacology·Mikael C Guzman-KarlssonJ David Sweatt
Jun 12, 2012·Neural Plasticity·Bridget N QueenanDaniel T S Pak
Sep 27, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mansi VithlaniStephen J Moss
Sep 29, 2011·The Journal of Physiology·Claire E J Cheetham, Kevin Fox
Aug 10, 2011·The Journal of Physiology·Timothy O'Leary, David J A Wyllie
May 24, 2016·Journal of Bodywork and Movement Therapies·Dorothea Blostein

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