Multiple myeloma associated with lactic acidosis

Leukemia & Lymphoma
Celalettin UstunPaul Dainer

Abstract

Type B lactic acidosis is rare among patients with malignant diseases. To date only one case report has documented lactic acidosis occurring in a patient with multiple myeloma (MM). Our patient, a 55-year-old black man, was diagnosed with stage IIIA immunoglobulin G-kappa (IgG-kappa) MM in September 1995. He was found to have severe lactic acidosis at the time of second relapse. During the terminal phase of his disease, he required multiple hospitalizations for management of lactic acidosis and other complications of his MM. No other cause of his elevated lactate levels was identified. Although type B lactic acidosis may more commonly occur in patients with leukemia or lymphoma, it may rarely present in patients with rapidly progressive and refractory MM.

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Citations

Oct 1, 2008·Journal of Veterinary Internal Medicine·J ElfenbeinA Woolums
Jun 14, 2013·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Patrick SiaJennifer A Fillaus
Apr 13, 2010·Critical Care Clinics·Christopher Vernon, Jennifer L Letourneau
Sep 27, 2012·Clinical Lymphoma, Myeloma & Leukemia·Patrick TangMojtaba Akhtari
Sep 8, 2005·Journal of Intensive Care Medicine·Pamela J Fall, Harold M Szerlip

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