PMID: 591115Jan 1, 1977

Multiple myeloma, IgA cryoglobulinemia and serum hyperviscosity in a dog

International Archives of Allergy and Applied Immunology
G VirellaJ Goudswaard

Abstract

Clinical signs of hyperviscosity syndrome in a 6-year-old dog included listlessness, polydipsia, anorexia, vomiting, and recurrent bleeding from the gums. Fundoscopy showed the typical retinal changes associated with this syndrome. A polymeric IgA cryoglobulin characterized in the dog's serum was later isolated and structurally studied. It was found to contain J chain but no secretory component. The heavy and light chains were covalently bound.

Citations

Jan 1, 1979·Comparative Immunology, Microbiology and Infectious Diseases·J GoudswaardJ A van der Donk
Jan 1, 1979·Comparative Immunology, Microbiology and Infectious Diseases·J GoudswaardA Noordzij
Jan 1, 1983·Veterinary Clinical Pathology·J G ZinklG K Saunders
Jan 1, 1977·Immunological Communications·P C MontgomeryG Virella
Jan 1, 1978·Scandinavian Journal of Immunology·J GoudswaardJ P Vaerman
Feb 9, 2010·The Journal of Small Animal Practice·C M ElwoodK Savary-Bataille
Jan 1, 1982·The Journal of Small Animal Practice·J W Finnie, C R Wilks
Oct 6, 2000·Journal of the American Veterinary Medical Association·F H HickfordT Schermerhorn
Sep 10, 2003·Journal of the American Veterinary Medical Association·Sarah J LautzenhiserRobert L Goring

Related Concepts

Blood Viscosity
Cryoproteins
Canis familiaris
SDS-PAGE
IgA2
Immunoelectrophoresis
Multiple Myeloma
Plasma Cell Dyscrasia
Secretory Component

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.