Multiple opioid receptor-like genes are identified in diverse vertebrate phyla

FEBS Letters
X LiC J Evans

Abstract

Polymerase chain reaction was used to determine whether opioid receptor-like sequences are present in species from the protostome and deuterostome branches of the metazoan kingdom. Multiple opioid receptor-like sequences were found in all vertebrates, but no specific fragments were obtained from any invertebrates. Delta, mu, kappa and ORL-1 receptors were identified from bovine DNA, and three different opioid receptor-like fragments were identified from the other vertebrates analyzed. The data suggest that the opioid receptor gene family has been highly conserved during vertebrate evolution and that, even in the primitive jawless fish, multiple members of the opioid receptor family appear to be present.

References

Dec 1, 1979·Neuroscience Letters·R MartinK H Voigt
Dec 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·B L KiefferC G Hirth
Dec 28, 1992·Science·C J EvansR H Edwards
Jun 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·K RichterG Kreil
Apr 15, 1994·Journal of Neuroscience Research·M E AboodQ Tao
Jun 30, 1995·The Journal of Biological Chemistry·D L KaufmanY R Xia
May 1, 1994·Neuropeptides·S BenyheE A Barnard
Aug 15, 1994·Biochemical and Biophysical Research Communications·E ManssonD Yang
Nov 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·F MengH Akil
Dec 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·G B StefanoN N Abumrad
Jan 1, 1996·Annual Review of Pharmacology and Toxicology·P A ZakiF Porreca

❮ Previous
Next ❯

Citations

Aug 11, 1999·The Journal of Comparative Neurology·A PorterosR E Rodríguez
Dec 13, 2000·Brain Research. Molecular Brain Research·A BarralloR E Rodríguez
Jun 25, 1999·Brain Research. Molecular Brain Research·M L Andria, E J Simon
Oct 4, 2008·Proceedings of the National Academy of Sciences of the United States of America·Susanne DreborgDan Larhammar
Mar 22, 2002·The Journal of Pharmacology and Experimental Therapeutics·Leslie C NewmanCraig W Stevens
Dec 30, 2008·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Maya S KummrowMichael Court
May 3, 2007·Journal of the American Veterinary Medical Association·Kurt K SladkyStephen M Johnson
Jul 17, 2008·Journal of the American Veterinary Medical Association·Kurt K SladkyStephen M Johnson
Mar 11, 2009·Frontiers in Bioscience (Landmark Edition)·Craig W Stevens
Jan 26, 2011·General and Comparative Endocrinology·B M L Verburg-van KemenadeM Chadzinska
Jul 22, 2010·Autonomic Neuroscience : Basic & Clinical·Charles H V Hoyle
Jul 22, 2010·Journal of Veterinary Pharmacology and Therapeutics·S N WambuguT I Kanui
Jul 17, 2010·Annals of the New York Academy of Sciences·Jazalle McClendonRobert M Dores
Nov 4, 2008·Brain, Behavior, and Immunity·Magdalena ChadzinskaB M Lidy Verburg-van Kemenade
Oct 22, 2008·Molecular Phylogenetics and Evolution·M Javier Herrero-Turrion, Raquel E Rodríguez
Aug 16, 2001·Molecular Biology and Evolution·A GermotS Mazan
Aug 25, 2020·Journal of Neuroscience Research·Alden Y HuangChristopher J Evans
Jul 15, 1999·Biochemical and Biophysical Research Communications·S BenyheA Borsodi
Jan 22, 1998·Biochemical and Biophysical Research Communications·M RingvallD Larhammar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.