Multiple origins of green blood in New Guinea lizards

Science Advances
Zachary B RodriguezChristopher C Austin

Abstract

Several species of lizards from the megadiverse island of New Guinea have evolved green blood. An unusually high concentration of the green bile pigment biliverdin in the circulatory system of these lizards makes the blood, muscles, bones, tongue, and mucosal tissues bright green in color, eclipsing the crimson color from their red blood cells. This is a remarkable physiological feature because bile pigments are toxic physiological waste products of red blood cell catabolism and, when chronically elevated, cause jaundice in humans and all other vertebrates. Although these lizards offer a promising system to examine the evolution of extraordinary physiological characteristics, little is known about the phylogenetic relationships of green-blooded lizards or the evolutionary origins of green blood. We present the first extensive phylogeny for green-blooded lizards and closely related Australasian lizards using thousands of genomic regions to examine the evolutionary history of this unusual trait. Maximum likelihood ancestral character state reconstruction supports four independent origins of green blood. Our results lay the phylogenetic foundation necessary to determine the role, if any, of natural selection in shaping this enigma...Continue Reading

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Citations

May 5, 2020·Molecular Biology and Evolution·Bui Quang MinhRobert Lanfear
Jul 15, 2020·Proceedings of the National Academy of Sciences of the United States of America·Carlos TaboadaSara E Bari
Jan 18, 2019·Optics Express·Jung Woo LeemYoung L Kim
Feb 6, 2020·Molecular Phylogenetics and Evolution·Alex SlavenkoShai Meiri

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Software Mentioned

Trimmomatic
MAFFT
II
R package ape
describe
simmap
geiger
Illumiprocessor
phytools
RAxML

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