Multiple Polychlorinated Biphenyl Transformation Systems in the Gram-Positive Bacterium Rhodococcus sp. Strain RHA1.

Applied and Environmental Microbiology
M SetoK Yano

Abstract

The cloned bphA gene of the polychlorinated biphenyl (PCB) degrader Rhodococcus sp. strain RHA1 was expressed in Rhodococcus erythropolis IAM1399 cells, resulting in the transformation of di-, tri-, and tetrachlorobiphenyls. Disruption of the bphA1 gene in RHA1 resulted in a lack of growth on biphenyl and a loss of PCB transformation activity. However, the bphA1 insertion mutant of RHA1, designated RDA1, retained the ability to transform PCB congeners when grown on ethylbenzene as its carbon source. It also transformed 4-chlorobiphenyl to 4-chlorobenzoate, although it was suspected to be deficient in bphB and bphC gene activities as well as bphA. This suggested that an alternative PCB degradation system distinct from the one encoded by the cloned bph genes was present.

References

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Citations

Mar 2, 2011·Canadian Journal of Microbiology·Katherine C YamLindsay D Eltis
Jul 31, 2012·Applied and Environmental Microbiology·Toju IinoMasao Fukuda
Sep 1, 2015·Applied and Environmental Microbiology·Daisuke KasaiMasao Fukuda
Apr 26, 2008·Archives of Microbiology·Juana María Navarro-LlorensJulián Perera
Nov 8, 2011·Applied and Environmental Microbiology·Hao-Ping ChenLindsay D Eltis
Nov 22, 2014·Bioscience, Biotechnology, and Biochemistry·Kenichi YanoNoritaka Iwai
Sep 8, 2006·Applied and Environmental Microbiology·Edmilson R GonçalvesWilliam W Mohn
Sep 22, 2007·Applied Microbiology and Biotechnology·Arno ReinUlrich Gosewinkel Karlson
Feb 2, 2016·Bioscience, Biotechnology, and Biochemistry·Yuki AtagoHirofumi Hara
Jul 20, 2007·Molecular Microbiology·Sachi Okamoto, Lindsay D Eltis
Jun 22, 2005·Journal of Bacteriology·Juana María Navarro-LlorensWilliam W Mohn
Mar 25, 2015·Current Microbiology·Shobha K Jayanna, Devaraja Gayathri
Mar 12, 2019·The Journal of General and Applied Microbiology·Saori WatahikiMasao Fukuda
Jun 11, 2021·Chemosphere·Petrić InesUdiković-Kolić Nikolina
May 4, 2011·Biochemistry·Joseph N RobertsLindsay D Eltis
Jun 19, 2008·Journal of Bioscience and Bioengineering·Kensuke Furukawa, Hidehiko Fujihara

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