PMID: 9543667Apr 17, 1998Paper

Multiple polypoid lesions of primary mucosa-associated lymphoid-tissue lymphoma of colon

Histopathology
Y YatabeT Suchi

Abstract

This study was focused on unusual cases of mucosa-associated lymphoid tissue (MALT) lymphoma presenting with multiple polypoid lesions of the colon and rectum with a special reference to the differential diagnosis of mantle cell lymphoma. The lesions of these five cases grossly showed a segmental distribution of nodular protrusions in three patients and of innumerable small polyps in two. These patterns of involvement simulated those of multiple lymphomatous polyposis, known as the gastrointestinal presentation of mantle cell lymphoma (MCL), and caused a differential diagnostic problem between MALT lymphoma and MCL, which have different prognostic and therapeutic implications. Their histological features are almost indistinguishable from each other, especially in the small biopsy specimens via endoscope. The most important procedure for their differentiation is cyclin D1 immunohistochemistry and its negative reaction provides strong indication of MALT lymphoma. Of interest, one case showed a rare karyotypic abnormality of t(11;18)(q21;q21), which has been reported specifically in MALT lymphoma. This study has indicated that the multiple polypoid lesions of the colon occur not only in MCL, but also in MALT lymphoma, making diffe...Continue Reading

References

Mar 1, 1992·Genes, Chromosomes & Cancer·C A GriffinR Mann
Jan 1, 1992·Cancer Genetics and Cytogenetics·A C WotherspoonP G Isaacson
Nov 1, 1990·American Journal of Clinical Pathology·A C WotherspoonP G Isaacson
Jun 1, 1986·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P L TriozziJ P Gockerman
Jul 1, 1984·Histopathology·P G IsaacsonS G Subbuswamy
Oct 1, 1994·Cancer Genetics and Cytogenetics·J Whang-PengD L Longo
Apr 1, 1993·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R A ShivdasaniG S Pinkus
Apr 1, 1996·The American Journal of Surgical Pathology·M J MoynihanD D Weisenburger
Apr 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G A VeldersJ H Van Krieken
May 1, 1996·Virchows Archiv : an International Journal of Pathology·M de NictolisJ Prat

❮ Previous
Next ❯

Citations

Jun 4, 2005·Gastrointestinal Endoscopy·José Miguel EstebanJuan Andrés Ramírez Armengol
Apr 14, 2000·Journal of Gastroenterology and Hepatology·R TakenakaT Tsuji
Sep 12, 2008·World Journal of Gastroenterology : WJG·Marco PennazioRoberto de Franchis
May 29, 2009·Journal of Clinical and Experimental Hematopathology : JCEH·Masaru KojimaHirokazu Nakamine
Oct 6, 2011·Archives of Pathology & Laboratory Medicine·Jerome S Burke
Sep 13, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Sangeet GhaiMark Stephens
Aug 11, 2000·Applied Immunohistochemistry & Molecular Morphology : AIMM·H W KorinM Younes
Jan 20, 2010·Journal of Gastroenterology·Shuji YamamotoTsutomu Chiba
Mar 9, 2010·Best Practice & Research. Clinical Gastroenterology·Agnes Ruskoné-Fourmestraux, Josée Audouin
Jan 22, 2008·Gastrointestinal Endoscopy·Job H C PetersMaarten A J M Jacobs
Nov 25, 2003·American Journal of Hematology·Shigeki TomitaTakahiro Fujimori
Oct 2, 2004·Current Problems in Diagnostic Radiology·José Antonio NarváezAlberto Fernández-Sevilla
Mar 1, 2015·Abdominal Imaging·Akshay D BahetiNikhil H Ramaiya
Jun 28, 2012·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Hyeonsu ParkSanghui Park
Apr 15, 2010·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Jong Hyeok Park, Jung Hwan Lee
Nov 18, 2014·World Journal of Gastrointestinal Endoscopy·Andreia Albuquerque

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.