PMID: 39121Jul 1, 1979

Multiple, prolonged actions of neuroendocrine bag cells on neurons in Aplysia. I. Effects on bursting pacemaker neurons

Journal of Neurophysiology
E MayeriS B Simon

Abstract

1. The bag cells are a group of neuroendocrine cells located in the abdominal ganglion of Aplysia. Accumulated evidence suggests they synthesize and release egg-laying hormone (ELH), a peptide that induces egg laying. In this and the following paper (37) we describe five types of prolonged neural responses in cells of the isolated abdominal ganglion that are produced by stimulated bag cell activity. 2. Prolonged, 5- to 40-min bursts of spike activity were triggered in the normally silent bag cells by local stimulation of one of the bag cell clusters with brief, 0.6- to 2-strains of pulses. This local stimulation minimized the possible effects of the stimulus on other ganglion cells and initiated bag cell activity similar to what has been recorded in intact animals at the initiation of egg laying. 3. Following onset of triggered bag cell activity there is an increase in the amplitude of the bursting pacemaker potential in cell R15 that results in augmented bursting activity in this autoactive cell for up to 3 h. The increase begins in less than 1 min and reaches a maximim after 8--20 min. In two other bursting pacemaker cells, L3 and L6, there is a second type of response, slow inhibition, consisting of a smoothly graded hyperpo...Continue Reading

References

Mar 1, 1990·Behavior Genetics·L DesGroseillers
Feb 1, 1989·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·G P FergusonH M Pinsker
Jan 1, 1987·Journal of Neurobiology·R O Brown, E Mayeri
Jun 1, 1981·Cellular and Molecular Neurobiology·C FlickerJ A Hobson
Jun 23, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Elena V RomanovaJonathan V Sweedler
Feb 11, 2012·Journal of Neurophysiology·Sean H White, Neil S Magoski
Sep 5, 2014·Journal of Neurophysiology·Zahra DargaeiNeil S Magoski
Feb 1, 1992·Journal of Neurobiology·C LandryL DesGroseillers
Sep 15, 1987·Experientia·J Koester, U T Koch

Related Concepts

Periodicity
Neural Inhibition
Neurons
Synaptic Transmission
Oviposition
Ganglia
Electrophysiology (Science)
Neurohormones
Neurosecretion
Aplysia

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