Multiple-response optimization of the acidic treatment of the brown alga Ecklonia radiata for the sequential extraction of fucoidan and alginate

Bioresource Technology
Andrew John LorbeerWei Zhang

Abstract

The aim of this study was to optimize the acidic treatment of the brown alga Ecklonia radiata in order to extract fucoidan and facilitate the efficient sequential extraction of alginates. Response surface methodology was used to determine the effects of the temperature, pH, and duration of the acidic treatment on fucoidan yield, alginate extractability, and the molecular weight of sequentially extracted alginates. Desirability functions were then used to predict the best overall combinations of responses. The most desirable compromise allowed for the recovery of a fucoidan-rich fraction with a yield of 3.75% (w/w of alga) and the sequential extraction of alginates having an average molecular weight of 730kDa at a yield of 44% (w/w of alga), with low cross-contamination between the products. The optimized acidic treatment could form the basis of an industrial biorefinery process for the production of both fucoidan and alginate.

References

May 12, 2009·International Journal of Biological Macromolecules·César G GomezMarcelo A Villar
Nov 18, 2011·Applied Microbiology and Biotechnology·V K MoryaEun-Ki Kim
Nov 29, 2012·Bioresource Technology·Kyung A JungJong Moon Park
Apr 5, 2014·Bioresource Technology·Paula Pérez-LópezM Teresa Moreira

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Citations

Sep 7, 2016·International Journal of Molecular Sciences·Shengye WangEric Guibal
Aug 16, 2019·Journal of Food Science and Technology·Sugiono SugionoSimon Bambang Widjanarko
Aug 28, 2018·Journal of Applied Phycology·Joe A GallagherMichael K Theodorou
Nov 20, 2016·Applied Biochemistry and Biotechnology·Hyun Jin Ryu, Kyeong Keun Oh
Apr 2, 2017·International Journal of Biological Macromolecules·Niloofar Jokar BorazjaniMasoud Rezaei
Jun 18, 2021·3 Biotech·Kanika AroraSaurabh Kulshrestha

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