Multiple Sclerosis.

Annals of Internal Medicine
Michael J Olek

Abstract

Many groundbreaking advances have occurred in the field of multiple sclerosis since this series last reviewed the disorder in 2014. The U.S. Food and Drug Administration has approved 7 new medications for relapsing-remitting multiple sclerosis and approved the first medication for primary progressive multiple sclerosis. The McDonald criteria for diagnosing multiple sclerosis were updated in 2017. New blood tests can now differentiate patients with multiple sclerosis from those with neuromyelitis optica spectrum disorder, and 3 new medications have been approved specifically for the latter disorder. Also, new medications for treating the symptoms of multiple sclerosis have been introduced.

References

Apr 29, 1998·Brain : a Journal of Neurology·J I O'RiordanD H Miller
Dec 25, 2002·Neurology·Olivier T RutschmannUNKNOWN Immunization Panel of the Multiple Sclerosis Council for Clinical Practice Guidelines
Mar 3, 2006·The New England Journal of Medicine·Chris H PolmanUNKNOWN AFFIRM Investigators
Apr 20, 2006·The British Journal of Ophthalmology·J de la Cruz, M J Kupersmith
May 11, 2006·Annals of Neurology·Talat IslamThomas M Mack
Jun 21, 2008·Lancet Neurology·Rohit BakshiMassimo Filippi
Jun 13, 2009·Blood Purification·Corinna TrebstMartin Stangel
Aug 10, 2010·Annals of Neurology·Steve SimpsonIngrid van der Mei
Sep 22, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Jorge CorrealeMaría I Gaitán
Mar 25, 2011·Journal of Neurology·Mauricio F Farez, Jorge Correale
Mar 1, 2012·Journal of Neurology, Neurosurgery, and Psychiatry·Merja Soilu-HänninenMassimo Filippi
May 18, 2012·The New England Journal of Medicine·Gary BloomgrenCarmen Bozic
Aug 29, 2012·Annals of Neurology·Ellen M MowryDaniel Pelletier
Sep 21, 2012·The New England Journal of Medicine·Ralf GoldUNKNOWN DEFINE Study Investigators
Jan 17, 2013·Journal of Neuroinflammation·Sven Jarius, Brigitte Wildemann
Mar 8, 2013·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Peter LeeMeena Subramanyam
Mar 27, 2013·Nature Reviews. Neurology·Martin StangelHayrettin Tumani
Oct 1, 2013·Nature Genetics·UNKNOWN International Multiple Sclerosis Genetics Consortium (IMSGC)Jacob L McCauley
Oct 23, 2013·Multiple Sclerosis : Clinical and Laboratory Research·C Ramo-TelloJ Costa
Jan 30, 2016·Lancet Neurology·Massimo FilippiUNKNOWN MAGNIMS Study Group
Dec 16, 2017·Neurology and Therapy·Martina B SintzelAnthony T Reder
Dec 26, 2017·Lancet Neurology·Alan J ThompsonJeffrey A Cohen
Aug 15, 2018·Eye and Brain·Fiona Costello, Jodie M Burton
Feb 17, 2019·Neurology·Mitchell T WallinUNKNOWN US Multiple Sclerosis Prevalence Workgroup
Apr 25, 2020·Revista de neurologia·L Costa-FrossardEn Representación Del Grupo de Estudio de Enfermedades Desmielinizantes de la Comunidad Autónoma de Madrid En Representación Del Grupo de Estudio de Enfermedades Desmielinizantes de la Comunidad Autónoma de Madrid
May 22, 2020·Frontiers in Immunology·Andrei MicleaRobert Hoepner
Sep 17, 2020·Brain : a Journal of Neurology·Maria Pia AmatoMaria Trojano
Nov 24, 2020·Neurologic Clinics·Carolyn Goldschmidt, Marisa P McGinley
Nov 24, 2020·Neurologic Clinics·Asya Izraelit WallachIlya Kister
Jan 17, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Enrique Gómez-FigueroaJosé Flores-Rivera
Jan 22, 2021·Neurology·Giacomo BoffaUNKNOWN Italian BMT-MS study group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.