PMID: 2510046Oct 1, 1989Paper

Multiple spinal neurinomas without von Recklinghausen's disease: report of three cases

No shinkei geka. Neurological surgery
S NishiH Sakaida

Abstract

Multiple spinal tumors are relatively rare and account for from only 1.2 to 9.5% of all spinal tumors. Half of the multiple spinal tumors are accompanied with von Recklinghausen's disease. Since March 1983, we have encountered 31 spinal tumors including 11 neurinomas, three of which were multiple and showed no manifestations of von Recklinghausen's disease. The incidence of multiple spinal tumors was 9.7% in our series. Altogether, 40 cases of multiple spinal neurinomas without von Recklinghausen's disease have been reported including our three cases. According to those 40 cases, much neurinomas occur 5 times more frequently in men than in women, and they are found predominantly in the lumbosacral region. In the present paper, we describe three cases of multiple spinal neurinomas, and compare the results of several neuroradiological examinations. Myelography was the most reliable method to determine whether or not the tumors were multiple. However, in cases where myelography was completely blocked out, other neuroradiological methods such as metrizamide-CT scan or MRI with Gd-DTPA intravenous injection were able to bring us information concerning multiplicity.

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.