PMID: 9428798Jan 15, 1998Paper

Multiple subphases of DNA replication in Chinese hamster ovary (CHO-K1) cells

DNA and Cell Biology
Gaspar BanfalviM W Chou

Abstract

Replicative DNA synthesis has been measured throughout the S phase in synchronized populations of Chinese hamster ovary cells. When exponentially growing, cells in suspension cultures were subjected to counterflow centrifugal elutriation and the resolution power was increased the biphasic replication profile has been resolved and multiple subphases were distinguished. These replication peaks, termed replication checkpoints, are distributed evenly throughout the S phase. The replication checkpoints have been characterized by their average C values corresponding to 2.05, 2.12, 2.2, 2.45, 2.6, 2.8, 2.95, 3.15, 3.3, 3.45, and 3.85.

References

Jan 1, 1979·Methods in Enzymology·J W Gray, P Coffino
Feb 10, 1975·Biochimica Et Biophysica Acta·S SekiG C Mueller
Nov 3, 1989·Science·L H Hartwell, T A Weinert
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Citations

May 24, 2005·Apoptosis : an International Journal on Programmed Cell Death·G BanfalviA G Basnakian
Jan 30, 2007·Apoptosis : an International Journal on Programmed Cell Death·Gaspar BanfalviAlexei Basnakian
Jul 19, 2012·Bulletin of Experimental Biology and Medicine·I P ShabalkinA S Yagubov
Dec 10, 2013·Bulletin of Experimental Biology and Medicine·I P ShabalkinA S Yagubov
Nov 4, 2000·DNA and Cell Biology·M RehakG Banfalvi

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