Multiple transduction pathways regulate the sodium-extrusion gene PMR2/ENA1 during salt stress in yeast

FEBS Letters
J A Márquez, Ramón Serrano

Abstract

The yeast PMR2/ENA1 gene encodes an ATPase involved in sodium extrusion and induced by NaCl. At low salt concentrations (0.3 M) induction is mediated by the HOG-MAP kinase pathway, a system activated by non-specific osmotic stress. At high salt concentrations (0.8 M) induction is mediated by the protein phosphatase calcineurin and is specific for sodium. Protein kinase A and Sis2p/Hal3p modulate PMR2/ENA1 expression as negative and positive factors, respectively but Sis2p/Hal3p does not participate in the transduction of the salt signal. Salt stress decreases the level of cAMP and the resulting decrease in protein kinase A activity may contribute to HOG-mediated induction.

References

Oct 21, 1991·FEBS Letters·R HaroA Rodríguez-Navarro
Jan 1, 1991·Methods in Enzymology·D M Becker, L Guarente
Jan 1, 1991·Methods in Enzymology·F Sherman
Nov 1, 1987·Genes & Development·J NikawaM Wigler
Oct 1, 1995·Molecular and Cellular Biology·A FerrandoR Serrano
Mar 19, 1993·Science·J L BrewsterM C Gustin
Sep 1, 1993·Trends in Biochemical Sciences·J Kunz, M N Hall
Dec 1, 1994·Yeast·J M Thevelein
Aug 1, 1995·Molecular Microbiology·V J Miralles, R Serrano
Jan 1, 1996·International Review of Cytology·R Serrano
Oct 29, 1982·Science·J S Boyer

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Citations

Apr 1, 1999·Cell Biochemistry and Biophysics·C S Hemenway, J Heitman
Nov 5, 1999·Biochimica Et Biophysica Acta·B L PerssonJ Pattison
May 22, 2001·Molecular Microbiology·O KinclováH Sychrová
Jun 24, 1998·Proceedings of the National Academy of Sciences of the United States of America·E de NadalJ Ariño
Dec 18, 2001·Plant Physiology·F J Maathuis, D Sanders
Oct 31, 2006·Applied and Environmental Microbiology·Sonia Rodríguez-VargasFrancisca Randez-Gil
Jun 15, 2007·Applied and Environmental Microbiology·Joaquín PanaderoFrancisca Randez-Gil
Mar 5, 2005·Applied and Environmental Microbiology·Joaquin PanaderoJose Antonio Prieto
Oct 24, 2007·Eukaryotic Cell·Amparo Ruiz, Joaquín Ariño
Mar 10, 2006·Eukaryotic Cell·Maria Jose Hernandez-LopezFrancisca Randez-Gil
Mar 4, 2010·Microbiology and Molecular Biology Reviews : MMBR·Joaquín AriñoHana Sychrová
Jun 1, 2002·Microbiology and Molecular Biology Reviews : MMBR·Stefan Hohmann
Jun 28, 2012·PLoS Computational Biology·Matthias KahmMaik Kschischo
Jan 24, 2013·PLoS Computational Biology·Ruian KeKen Haynes
Mar 1, 2012·Genetics·Maribel MarquinaJoaquín Ariño
Jun 29, 2014·International Journal of Food Microbiology·Tikam Chand DakalPaolo Giudici
Sep 26, 2015·Biochimica Et Biophysica Acta·Leticia BaccariniPaula Portela
Dec 24, 2009·The Biochemical Journal·Jofre Ferrer-DalmauAntonio Casamayor
Jul 14, 2011·The Biochemical Journal·Carlos CasadoJoaquín Ariño
Jan 9, 2015·PLoS Genetics·Sebastian TreuschLeonid Kruglyak

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