PMID: 8611401Apr 1, 1996Paper

Multiplicity of fibronectin-binding alpha V integrin receptors in colorectal cancer

British Journal of Cancer
M V AgrezD Sheppard

Abstract

Current data from in vitro and in vivo animal models indicate that fibronectin-binding integrin receptors expressed by colon cancer cells may regulate tumour growth. While individual members of the beta 1 subfamily of integrins have now been clearly identified in colorectal cancer, little information exists with respect to the alpha V subfamily. In the present study we show that alpha V can associate with multiple and different beta subunits capable of binding fibronectin in this tumour type. This is likely to have functional implications for growth and spread of colorectal cancer.

Citations

Dec 1, 1996·The Australian and New Zealand Journal of Surgery·M V Agrez
Jan 25, 2002·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·G J Thomas, P M Speight
May 7, 2002·International Journal of Cancer. Journal International Du Cancer·Jun NiuMichael V Agrez
Feb 13, 2004·The Journal of Biological Chemistry·Paul H WeinrebShelia M Violette
Oct 23, 2015·European Journal of Nuclear Medicine and Molecular Imaging·Nadia WithofsRoland Hustinx
Feb 22, 2002·Oncogene·Nuzhat AhmedMichael V Agrez
Apr 26, 2000·British Journal of Cancer·S HamidiH Larjava
Aug 24, 2017·Cancers·Sabine Raab-WestphalSimon L Goodman
Apr 3, 2001·International Journal of Cancer. Journal International Du Cancer·J NiuM Agrez
Nov 2, 2012·Cellular and Molecular Life Sciences : CMLS·Christina M DobsonLance Wells
Jul 27, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Mimoun NejjariJean-Yves Scoazec
Jan 18, 2019·International Journal of Cancer. Journal International Du Cancer·Susan BengsMichael Scharl
Aug 26, 1998·Biochemical and Biophysical Research Communications·J NiuM Agrez
Jun 16, 2001·The Journal of Investigative Dermatology·G J ThomasJ F Marshall
Jul 10, 2001·The Journal of Investigative Dermatology·G J ThomasJ F Marshall
Oct 24, 2006·Experimental Cell Research·Merit E Reyes-ReyesSteven K Akiyama
Feb 6, 2007·European Journal of Cell Biology·Francis FouchierSerge Champion
Nov 6, 2007·Clinical Oncology : a Journal of the Royal College of Radiologists·Z-Y ZhangJ Niu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.