Multireader, multicase receiver operating characteristic methodology: a bootstrap analysis

Academic Radiology
D D DofrmanR V Lenth

Abstract

We evaluated by bootstrapping the conclusions obtained by the Dorfman-Berbaum-Metz (DBM) receiver operating characteristic (ROC) method and by the Toledano-Gatsonis (TG) method on a well-known data set. We bootstrapped in two ways, resampled cases while holding readers fixed and resampled both cases and readers. When an analysis of variance of pseudovalues implies that reader variance and all random interactions with treatment are essentially zero, then case-resampling bootstrap and the DBM and TG methods should give the same results. Case-resampling bootstrap and the DBM and TG methods did give highly similar results for both individual readers and the averages over all readers. Both the case-resampling bootstrap and the reader-case resampling bootstrap gave smaller standard errors for group than for individual reader means, thereby providing evidence for a trade-off of readers and cases with regard to precision and power in this data set. Case-resampling bootstrap provides some justification for the DBM and TG methods.

References

Jan 1, 1984·Medical Decision Making : an International Journal of the Society for Medical Decision Making·B J McNeil, J A Hanley
Dec 1, 1993·Aging : Clinical and Experimental Research·A Toledano

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Citations

Jan 1, 2008·Radiological Physics and Technology·Charles E Metz
Nov 27, 2002·Academic Radiology·Robert F WagnerWilliam M Sacks
Jun 17, 2003·Journal of the American Medical Informatics Association : JAMIA·Wendy Webber ChapmanMichael M Wagner
Jun 14, 2002·Academic Radiology·Elizabeth A Krupinski, Hans Roehrig
Nov 6, 2012·Academic Radiology·Demissie Alemayehu, Kelly H Zou
Aug 13, 2011·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Allison L ZwingenbergerCalvin F Nodine
Oct 31, 2006·Academic Radiology·Kevin S Berbaum
Feb 1, 1997·Academic Radiology·D D DorfmanH Abu Dagga
Jan 1, 1999·Statistical Methods in Medical Research·C A Beam

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