Multislice T1-weighted hybrid RARE in CNS imaging: assessment of magnetization transfer effects and artifacts

Journal of Magnetic Resonance Imaging : JMRI
E R MelhemE K Yucel

Abstract

Using a T1-weighted hybrid rapid acquisition with relaxation enhancement (RARE) MR sequence that implements an echo-to-view mapping scheme termed "low-high profile order," we evaluated signal intensity changes in different brain tissues as a function of number of slices, interslice gap, and echo train length (ETL). We also measured phase-encode and frequency-encode noise as well as blurring artifacts along the phase-encode direction as a function of ETL. Off-resonance magnetization transfer effects were demonstrated to be responsible for signal intensities changes in white matter and gray matter when using multislice techniques. These effects are amplified by increasing the number of slices and ETL. Due to the nature of the implemented echo-to-view mapping scheme, no on-resonance magnetization transfer effects were observed from the intraslice echo train. Selective background (white matter and gray matter) suppression in multislice T1-weighted hybrid RARE, secondary to off-resonance magnetization transfer effects, may provide better contrast resolution of enhancing central nervous system (CNS) lesions at much shorter scan time as compared to conventional spin-echo T1-weighted sequences. This improvement in contrast resolution a...Continue Reading

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Oct 21, 2000·Investigative Radiology·V Mlynárik, S Trattnig
Mar 15, 2006·Magnetic Resonance Imaging Clinics of North America·Mark C DeLano, Charles Fisher
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Sep 12, 2002·Physics in Medicine and Biology·Tosiaki MiyatiKazuo Yamada

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