Sep 1, 1992

Multivariate analyses of CT findings in typical schizophrenia and atypical psychosis

The Japanese Journal of Psychiatry and Neurology
T HayashiT Sekine


In order to investigate the brain morphological differences between typical schizophrenia and atypical psychosis, the brain CTs of 41 patients with typical schizophrenia, 27 patients with atypical psychosis (ATP), and 20 controls were examined. The schizophrenics had larger values for 9 CT indices, i.e., interhemispheric fissure (IHF) index, VBR, 2 lateral ventricles (L-V) and 3rd ventricle (III-V) indices, and 4 sylvian fissure (SF) indices, while the values of ATP patients for 3 SF indices were greater than for the controls. Moreover, the schizophrenics had greater III-V and L-V indices than the ATP patients. The correlation matrix of CT indices indicates that the III-V index correlated well with the other CT indices, whereas the VBR, IHF and right SF indices did not. Therefore, it was speculated that there might be 3 subgroups, each of which has a main focus of alteration in the above-mentioned regions. Therefore, all the cases were divided by means of a cluster analysis into 5 groups. Group I, which contained mainly normal controls, and Group II, which consisted mainly of atypical psychosis patients, had no abnormal CT findings. Group III, which comprised mainly ATP patients and paranoid type schizophrenics, had right SF en...Continue Reading

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Mentioned in this Paper

Organic Mental Disorders, Psychotic
Differential Diagnosis
Multivariate Analysis
Tomography, X-Ray Computerized Axial
Schizophrenic Psychology
Psychotic Disorders
Factor Construct Rating Scales (Fcrs)
Schizophreniform Disorders

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