Multivessel Occlusion in Patients Subjected to Thrombectomy: Prevalence, Associated Factors, and Clinical Implications

Stroke; a Journal of Cerebral Circulation
Johannes KaesmacherJan Gralla

Abstract

Patients with embolic large-vessel occlusion may present with additional coincidental acute occlusions within or distant from the involved territory, referred to as multivessel occlusion (MVO). Purpose of this study was to assess prevalence of MVO, associated factors, and clinical relevance in patients undergoing endovascular stroke treatment. Image data of consecutive endovascular candidates (n=720) with direct access to angiography were extracted from a prospective registry. Prevalence of MVO was assessed with multimodal magnetic resonance imaging/computed tomography and confirmed by intra-arterial angiography. Explorative analysis of associated factors and clinical relevance was evaluated using multivariable logistic regression including variables with P<0.15 in univariate comparison. Good functional outcome was defined as modified Rankin Scale score ≤2 at day 90. MVO was present in 10.7% of patients (95% confidence interval [CI], 6.4%-13.0%). Two, 3, and 4 concomitant occlusions were found in 80.5%, 16.9%, and 2.6% of MVO cases, respectively. Detection rate on initial radiological report was 54.5%. Downstream MVO was present in around one third of MVO (n=27/77, 35.1%), whereas all other MVO (n=50/77, 64.9%) occurred in diff...Continue Reading

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Citations

Aug 20, 2020·Stroke; a Journal of Cerebral Circulation·Simon EscalardMichel Piotin
Jul 14, 2020·Stroke; a Journal of Cerebral Circulation·Johannes KaesmacherVolker Maus
May 30, 2020·Stroke; a Journal of Cerebral Circulation·Simon EscalardMichel Piotin
Oct 1, 2020·Stroke; a Journal of Cerebral Circulation·Johannes KaesmacherUrs Fischer
Jan 15, 2019·Acta neurologica Belgica·Delphine LondonFabrice C Deprez
Jul 15, 2020·Journal of Thrombosis and Thrombolysis·Ying-Kiat TanBenjamin Y Q Tan
Jan 21, 2021·Stroke; a Journal of Cerebral Circulation·Mayank GoyalJohanna Maria Ospel
Nov 12, 2020·Brain, Behavior, & Immunity Health·Hisham ElkhiderKrishna Nalleballe

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