PMID: 2112165May 1, 1990Paper

Mupirocin: a new topical antibiotic

Journal of the American Academy of Dermatology
J J Leyden

Abstract

One hundred fifty-three strains of Staphylococcus aureus recovered from infected eczema frequently demonstrated resistance to multiple antibiotics. Penicillin and ampicillin resistance was extremely frequent (88%), methicillin resistance was found in nearly 14% of strains, and erythromycin and tetracycline resistance was present in 16%. S. aureus strains were uniformly sensitive to vancomycin, mupirocin, and cephalosporins. Experimental infections in human volunteers showed topical therapy with 2% mupirocin was more effective than oral erythromycin in suppression of both S. aureus and Streptococcus pyogenes.

References

Jun 1, 1977·Archives of Dermatology·R AlyH R Shinefield
Jan 1, 1977·The Journal of Infectious Diseases·A S RichmondJ J Rahal
May 1, 1977·The British Journal of Dermatology·P J Frosch, A M Kligman
Apr 1, 1982·The Journal of Infectious Diseases·J P Myers, C C Linnemann

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Citations

Feb 16, 2000·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·M O Taskapan, P Kumar
Aug 11, 2004·American Journal of Clinical Dermatology·Iain B Gosbell
Jun 15, 2010·Burns : Journal of the International Society for Burn Injuries·Jessie S GlasserClinton K Murray
Sep 1, 1991·The Journal of Hospital Infection·B Slocombe, C Perry
Nov 1, 1995·The Journal of International Medical Research·N El Ferghani
Aug 1, 1994·Postgraduate Medicine·Steven M Hacker
Mar 2, 2006·Annales de dermatologie et de vénéréologie·J Mazereeuw-Hautier

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