PMID: 8586787Nov 1, 1995Paper

Mupirocin resistance in coagulase-negative staphylococci, after topical prophylaxis for the reduction of colonization of central venous catheters

The Journal of Hospital Infection
A Zakrzewska-BodeJ A Hoogkamp-Korstanje

Abstract

Topical mupirocin was routinely applied to insertion sites of central venous catheters (CVC) of neonates in a neonatal intensive care unit. After five years, mupirocin resistance was recorded in 42% of clinical isolates of coagulase-negative staphylococci (CNS). This decreased to 21% during a mupirocin-free interval of five months. We performed a prospective study on the significance of mupirocin use on the staphylococcal skin flora of 15 newly admitted neonates. During treatment, mupirocin-susceptible strains were replaced by highly resistant ones. After treatment, all but one neonate harboured at least one resistant strain; 29% of all strains were moderately resistant (mupirocin minimum inhibitory concentrations (MICs) 16 mg/L) and 55% were highly resistant (MICs > 1024 mg/L). One CVC (7%) became colonized with a resistant strain. One year after stopping routine mupirocin application the incidence of resistance had dropped to 13%; CVC colonization was recorded in 2.4%.

References

Jun 9, 1977·The New England Journal of Medicine·D G MakiH W Sarafin
May 5, 1990·Lancet·B D CooksonR J Redhead
Oct 1, 1990·Journal of Medical Microbiology·M RahmanI Phillips
May 1, 1990·Journal of the American Academy of Dermatology·J A MoyD M Carter

❮ Previous
Next ❯

Citations

Apr 1, 1997·Journal of Medical Virology·K I FalkI Ernberg
Jul 17, 2008·Annals of Hematology·Hans-Heinrich WolfUNKNOWN Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
Sep 21, 2004·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Fabio PaglialongaNicola Principi
May 15, 2002·Diagnostic Microbiology and Infectious Disease·L M DeshpandeUNKNOWN SENTRY Antimicrobial Surveillance Program Participants Group
Mar 23, 2011·Nature Reviews. Nephrology·Michiel G H Betjes
Mar 21, 2003·The New England Journal of Medicine·David C McGee, Michael K Gould
Apr 10, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Christopher J Crnich, Dennis G Maki
Dec 4, 2002·American Journal of Infection Control·Naomi P O'gradyUNKNOWN Healthcare Infection Control Practices Advisory Committee
Apr 7, 2007·Critical Care Medicine·Robert W Taylor, Ashok V Palagiri
Dec 17, 2004·Anaesthesia·A P Hall, W C Russell
Nov 13, 2008·Seminars in Dialysis·Gerald A Beathard, Aris Urbanes
Feb 24, 2006·Dermatology : International Journal for Clinical and Investigative Dermatology·Atsushi FukunagaTsuneo Nakamura
Mar 20, 2010·Critical Care : the Official Journal of the Critical Care Forum·Denis FrascaOlivier Mimoz
Jan 9, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M HentrichUNKNOWN Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology
Apr 5, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee (HICPAC)
Apr 7, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee (HICPAC) (Appendix 1)
Dec 3, 2014·The Surgical Clinics of North America·Mohamed F Osman, Reza Askari
Jul 31, 2012·Journal of Vascular and Interventional Radiology : JVIR·Donald L MillerUNKNOWN Society of Interventional Radiology
Feb 15, 2011·Infectious Disease Clinics of North America·David J Weber, William A Rutala
Jul 19, 2013·Seminars in Dialysis·Jonathan H Segal, Joseph M Messana
Jul 5, 2015·The Journal of Antimicrobial Chemotherapy·T PoovelikunnelH Humphreys
Oct 13, 2005·Expert Opinion on Pharmacotherapy·Michael J Sladden, Graham A Johnston
Sep 3, 2002·Chemistry & Biology·Paul N Danese
May 18, 2010·Neonatal Network : NN·Marie Corzine, Lynne D Willett
Nov 2, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J Carratalà
Jun 11, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jonas MarschallDeborah S Yokoe
Oct 9, 2008·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jonas MarschallDeborah S Yokoe
Jan 9, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee
Apr 29, 2011·American Journal of Infection Control·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee
Nov 17, 2012·The Surgical Clinics of North America·Peter J Rossi, Charles E Edmiston
Apr 14, 2017·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Marie GominetDavid Lebeaux
Apr 2, 2016·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Lori A DuesingAmy J Wagner
Nov 23, 2016·World Journal of Nephrology·Masashi SuzukiKyoji Moriya
Jul 2, 2005·The Neurologist·Kenneth HentschelDavid W Dodick
Nov 9, 2006·AACN Advanced Critical Care·Patricia J PosaKathleen M Vollman
May 18, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Matthew E FalagasIoannis A Bliziotis
Jul 31, 2010·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Victoria R WilliamsMatthew J Oliver
Feb 25, 2003·Cancer Control : Journal of the Moffitt Cancer Center·Gianluigi FerrettiSandro Barni
Dec 31, 2002·Journal of the American Society of Nephrology : JASN·Charmaine E LokJohn Conly
Jul 4, 2002·Journal of Critical Care·Naomi P O'Grady

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy & Infectious Diseases (ASM)

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Allergy & Infectious Diseases

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Related Papers

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
S RiuJ A Oliver
Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses
J RobbinsD N Korones
© 2021 Meta ULC. All rights reserved