PMID: 2112168May 1, 1990Paper

Mupirocin-resistant Staphylococcus aureus after long-term treatment of patients with epidermolysis bullosa

Journal of the American Academy of Dermatology
J A MoyD M Carter

Abstract

In a long-term, open study, 47 patients with epidermolysis bullosa were treated with topical 2% mupirocin (Bactroban) ointment to decrease bacterial infection and promote wound healing. This antibiotic is effective against gram-positive but not gram-negative organisms. No significant adverse effects were noted, although some patients have been treated for more than 4 years. We sought evidence in this patient population for the appearance of bacterial strains with decreased sensitivity to mupirocin. In five patients cultures from nonhealing wounds revealed Staphylococcus aureus resistance to mupirocin. Four of these patients were given oral antibiotics to which S. aureus was sensitive; they improved clinically, and cultures of their wounds became negative for pathogens.

References

Jan 1, 1984·Pediatric Dermatology·T W Cooper, E A Bauer

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Citations

Oct 24, 2003·Clinics in Dermatology·Ysabel M BelloLawrence A Schachner
Aug 26, 1998·The New England Journal of Medicine·F D Lowy
Feb 1, 1997·The Pediatric Infectious Disease Journal·G L Darmstadt
May 1, 1995·Clinical and Experimental Dermatology·M G Dunnill, R A Eady
Aug 22, 2006·Pediatric Dermatology·Adam I RubinKimberly D Morel
Mar 5, 2010·Pediatric Dermatology·Heather A Brandling-Bennett, Kimberly D Morel
Jun 1, 1995·Antimicrobial Agents and Chemotherapy·T M MortonG L Archer
Oct 21, 1999·International Journal of Antimicrobial Agents·J Turnidge, P Collignon
Jan 4, 1992·Lancet·B H Thiers
Sep 18, 2010·The Journal of Hospital Infection·A R CaffreyK L LaPlante
Aug 25, 2009·Journal of the American Academy of Dermatology·Jo-David Fine, Jemima E Mellerio
Sep 1, 1993·Journal of the American Academy of Dermatology·J B PardesV Falanga
Apr 14, 2007·Dermatologic Clinics·James Q Del Rosso, James J Leyden
Oct 23, 2009·Dermatologic Therapy·James Q Del Rosso, Grace K Kim
Sep 1, 1991·The Journal of Hospital Infection·B Slocombe, C Perry
Jun 1, 1995·The Journal of Hospital Infection·M W Casewell
Apr 1, 1994·The Journal of Hospital Infection·C A ChatfieldW C Noble
Sep 1, 1994·The Journal of Hospital Infection·S J DawsonD A Lewis
Apr 7, 2004·The Journal of Hospital Infection·C MarshallD Spelman
May 4, 1999·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·E E UdoS C Sanyal
Jun 28, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Julie KennerDuane Hospenthal
Apr 1, 1996·Dermatologic Clinics·A N Lin
Jan 6, 2006·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Aradhna SaxenaTatyana R Humphreys
Apr 1, 2015·Antimicrobial Agents and Chemotherapy·Nina K AntonovChristine T Lauren
Nov 26, 2015·Antimicrobial Agents and Chemotherapy·Catlyn BlanchardPaul M Dunman
Jul 25, 2003·Expert Opinion on Pharmacotherapy·David R P Guay

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