PMID: 2498274May 1, 1989Paper

Mureidomycins A-D, novel peptidylnucleoside antibiotics with spheroplast forming activity. II. Structural elucidation

The Journal of Antibiotics
F IsonoH Kuwano

Abstract

Structures of new antibiotics, mureidomycins (MRD's) A approximately D, were deduced from spectroscopic analyses and degradation studies. Two residues of m-tyrosine, one residue of 2-amino-3-N-methylaminobutyric acid (AMBA) and methionine are present in all components of the complex. Uracil is contained in MRD's A and C, while dihydrouracil in MRD's B and D. Methionine and m-tyrosine are connected through an ureido bond, and uracil or dihydrouracil is linked to AMBA via enamine sugar moiety. In addition, MRD's C and D contain a glycine residue at the N-terminal.

Citations

Nov 11, 1999·Medicinal Research Reviews·V J Lee, S J Hecker
Aug 18, 2012·Molecular BioSystems·Haihong HaoZonghui Yuan
Feb 26, 2014·Natural Product Reports·Takefumi KuranagaMasayuki Inoue
Mar 5, 2015·Chemical Society Reviews·Sherif I ElshahawiJon S Thorson
Mar 30, 2007·Chemical Communications : Chem Comm·Edmond GravelReynald Hocquemiller
May 8, 2016·Microbial Cell Factories·Yuanyuan ShiBin Hong
Sep 27, 2019·The Journal of Antibiotics·Hiroyuki Osada
Sep 1, 2019·The Journal of Antibiotics·Timothy D H Bugg, Rachel V Kerr
Jan 1, 1991·Critical Reviews in Biotechnology·C M Franco, L E Coutinho
Apr 11, 2007·The Journal of Antibiotics·Yunying XieHongzhang Xu
Feb 4, 2011·Chembiochem : a European Journal of Chemical Biology·Leonard KaysserBertolt Gust
Dec 19, 2008·Chembiochem : a European Journal of Chemical Biology·Sabine GrüschowRebecca J M Goss
Jun 14, 2014·Natural Product Reports·Fumitaka KudoTadashi Eguchi
Sep 10, 2011·Natural Product Reports·Daniel KrahnMarkus Kaiser
May 27, 2008·The Journal of Antibiotics·Yunying XieRuxian Chen
Mar 23, 2020·Journal of Molecular Biology·Ellene H Mashalidis, Seok-Yong Lee
Aug 12, 2005·Chemical Reviews·Alma VisoAida Flores
May 1, 1992·Antimicrobial Agents and Chemotherapy·F IsonoM Inukai
Dec 1, 1991·Pharmacology & Therapeutics·K Isono
Oct 1, 1993·Research in Microbiology·J J SanglierT Fehr
May 1, 1993·Antimicrobial Agents and Chemotherapy·M InukaiA Takatsuki
Feb 1, 1991·Antimicrobial Agents and Chemotherapy·F Isono, M Inukai
Jan 7, 2017·Chemical Reviews·Mireille MoutiezMuriel Gondry
Sep 9, 2016·Journal of Medicinal Chemistry·Michaela SerpiFabrizio Pertusati
Dec 27, 2011·The Journal of Organic Chemistry·Kazuya OkamotoAkira Matsuda
Jun 26, 2014·Journal of Natural Products·Yunying XieRuxian Chen
Mar 23, 2011·Journal of the American Chemical Society·Wenjun ZhangChristopher T Walsh

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