PMID: 6975942Nov 1, 1981Paper

Murine bone marrow cell line producing colony-stimulating factor

Proceedings of the National Academy of Sciences of the United States of America
K HarigayaR K Shadduck

Abstract

A cell line (H-1) derived from the adherent layer of a 14-wk-old Dexter bone marrow culture has been maintained as cloned and uncloned lines through 21 passages at the time of these studies. These cell lines develop many fat droplets as they age and become confluent. The uncloned line produces increasing amounts of colony-stimulating activity as the cells become confluent. Feeder layers or supernatants from the nonconfluent or confluent fat-laden cells stimulate the formation of greater numbers of colonies derived from cultures of colony-forming units (CFU) than does medium from L cell culture containing colony-stimulating factor (CSF). Antibody to the CSF-containing medium from L cell culture neutralizes the colony-stimulating activity, thus showing immunologic similarity to a known molecular species that stimulates colony production in a CFU culture that produces granulocyte or macrophage populations, or both.

References

Sep 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·G R Johnson, D Metcalf
Jun 1, 1977·Journal of Cellular Physiology·T M DexterL G Lajtha
Oct 7, 1976·Differentiation; Research in Biological Diversity·T D Allen, T M Dexter
Aug 1, 1970·Journal of Cellular Physiology·B L Pike, W A Robinson
Mar 1, 1980·Journal of Cellular Physiology·T M Dexter, R K Shadduck

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Citations

Apr 1, 1992·Journal of Cellular Physiology·A UmezawaJ Hata
Jun 26, 1987·Journal of Immunological Methods·P H HartJ J Finlay-Jones
Jan 1, 1992·Progress in Growth Factor Research·I Kawashima, Y Takiguchi
Oct 1, 1995·Critical Reviews in Oncology/hematology·N Fukushima, H Ohkawa
Mar 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·H M GarnettK Harigaya
May 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·K Harigaya, H Handa
Jun 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·D ZiporiT Oren
May 13, 2009·Blood·David L StachuraDavid Traver
Mar 24, 2007·Experimental Hematology·Nicholas DainiakLudwig Feinendegen
Oct 4, 2007·British Journal of Haematology·David J KuterRobert P Hasserjian
Jan 1, 1991·Critical Reviews in Oncology/hematology·J S Greenberger
Jan 1, 1985·Annals of the New York Academy of Sciences·T M FliednerA Raghavachar
Apr 9, 2013·International Journal of Pediatric Otorhinolaryngology·Hiromi KasagiHidetake Kurihara
Aug 1, 1995·Microscopy Research and Technique·M Rosendaal
Feb 1, 1984·Journal of Cellular Physiology·D ZiporiZ Malik
Apr 1, 1986·Journal of Cellular Physiology·S TsaiD G Nathan
Jan 1, 1983·Journal of Cellular Physiology·R K ShadduckT M Dexter

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