Murine encephalitozoonosis model for studying the host-parasite relationship of a chronic infection.

Infection and Immunity
E C Schmidt, J A Shadduck

Abstract

Encephalitozoon cuniculi caused chronic nonlethal infections in euthymic BALB/cAnN mice, whereas athymic BALB/cAnN-nu mice died from infection. Specific, anamnestic, transferable, and acquired responses against E. cuniculi were expressed by infected euthymic mice. Resistance to lethal disease appears to be T-cell dependent. Immune serum failed to protect infected athymic mice, whereas the transfer of T-enriched spleen cells from E. cuniculi-sensitized euthymic donors prevented lethal E. cuniculi infections in athymic mice. These findings indicate that murine encephalitozoonosis may be an excellent system for studies of a chronic infection in an immunologically well-characterized host.

References

Jul 1, 1979·Infection and Immunity·E Skamene, P A Kongshavn
Aug 1, 1978·Infection and Immunity·J E Bywater, B S Kellett
Sep 1, 1979·Infection and Immunity·L L SmrkovskiS G Reed
Nov 1, 1977·Infection and Immunity·G H CampbellF I Weinbaum
Dec 1, 1977·Infection and Immunity·M J LeffordG B Mackaness
Jul 1, 1978·Veterinary Pathology·J A ShadduckG T Robinson
Feb 11, 1975·The Journal of Experimental Medicine·J S Borges, W D Johnson
Dec 1, 1975·Experimental Parasitology·A Zuckerman
Apr 1, 1970·Canadian Journal of Microbiology·J E Bismanis
Oct 1, 1973·The Journal of Experimental Medicine·R E FowlesJ R David
Sep 1, 1969·Proceedings of the Society for Experimental Biology and Medicine·J S Remington, T C Merigan
Oct 1, 1973·European Journal of Immunology·M H JuliusL A Herzenberg
Sep 1, 1981·The Journal of Infectious Diseases·J Y NiederkornE C Schmidt
Jan 1, 1981·Transactions of the Royal Society of Tropical Medicine and Hygiene·L Hudson
Nov 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·K P Chang, J W Chiao
Jan 1, 1982·Annual Review of Medicine·O K Skinsnes
Jun 1, 1982·Infection and Immunity·B O AmoleH L Shear
Oct 1, 1981·Annals of Tropical Medicine and Parasitology·D J Ferguson, W M Hutchison
Jan 1, 1981·Transactions of the Royal Society of Tropical Medicine and Hygiene·C LeclercL Cheddid
Jun 1, 1970·Infection and Immunity·R J Patterson, G P Youmans

❮ Previous
Next ❯

Citations

Dec 12, 2003·Phytotherapy Research : PTR·D GarcíaF M Ubeira
Oct 18, 2006·Parasite Immunology·T Evering, L M Weiss
May 1, 1989·Parasite Immunology·J J LiuJ A Shadduck
Mar 23, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Magali MorettoImtiaz A Khan
Aug 17, 2005·Arquivos de neuro-psiquiatria·Maria Anete Lallo, Eduardo Fernandes Bondan
Jul 19, 2012·PLoS Pathogens·Magali M MorettoLouis M Weiss
Apr 11, 2015·Seminars in Immunopathology·Magali M MorettoImtiaz A Khan
Aug 1, 1988·The Journal of protozoology·N PetersonJ Shadduck
May 1, 1997·The Journal of Eukaryotic Microbiology·T TrammerH M Seitz
Nov 19, 2009·Parasitology Research·Frank Künzel, Anja Joachim
Mar 14, 2000·Veterinary Pathology·K Wasson, R L Peper
Dec 1, 2011·FEMS Microbiology Reviews·Kaya Ghosh, Louis M Weiss
Dec 10, 2002·Revista de saúde pública·Maria Anete LalloEduardo Fernandes Bondan
Nov 20, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Magali M MorettoImtiaz A Khan
Apr 29, 2014·Pathology Research International·Hafidh I Al-Sadi, Saevan S Al-Mahmood
Jul 17, 2020·Frontiers in Microbiology·Yinze HanZeyang Zhou
Dec 24, 2019·Medical Mycology·I F Abou-El-NagaS X A N X A El Achy
Jul 8, 2000·Microbes and Infection·E S DidierJ A Shadduck
May 23, 2001·Microbes and Infection·I A KhanL M Weiss
May 13, 1999·Veterinary Parasitology·M HalánováM Halán
May 5, 2001·International Journal for Parasitology·P BraunfuchsováJ Kopecký
Oct 1, 1994·Clinical Microbiology Reviews·R WeberR L Owen
Apr 1, 1989·Clinical Microbiology Reviews·J A Shadduck, E Greeley
Sep 26, 2017·Microbiology Spectrum·Bing Han, Louis M Weiss

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.