Murine erythroblasts do not contain histone H10

Developmental Biology
R W Lennox

Abstract

Histone H10, which is related to the avian erythrocyte-specific histone H5, is known to accumulate in the chromatin of differentiating murine erythroleukemia cells. However, H10 was less than approximately 1% of the H1 in the spleens of anemic or pregnant mice even when as many as 65% of the cells in the spleens were nucleated erythroid cells. The H1 complement of erythroid spleens was nevertheless quite different from that of normal spleens. I conclude that H10 has no major role in normal erythroid development in mammals.

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Citations

Sep 15, 2005·Histochemistry and Cell Biology·Nora N KostovaDimiter V Markov
Jan 1, 1990·Experimental Gerontology·Z A Medvedev, M N Medvedeva
May 25, 2005·The Journal of Biological Chemistry·John P H Th'ngMichael J Hendzel

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