PMID: 7334216Dec 1, 1981Paper

Murine immune memory to a TI-2 antigen, DNP-Ficoll: carrier-specificity, genetic enhancement and phenotypic dominant inheritance

Journal of Immunogenetics
C F SchottB Merchant

Abstract

C3H/HeN x NZB/BIN F1 mice were primed and challenged with DNP-Ficoll, a thymic independent (TI-2) antigen. They developed strong IgM and IgG carrier-specific memory responses: DNP-pneumococcal polysaccharide or DNP-haemocyanin challenge did not elicit memory responses. The IgG response component appeared to be inherited dominantly from the C3H/HeN parent. The IgM component resulted from genetic enhancement.

References

Jan 1, 1977·Immunological Reviews·D E MosierW E Paul
May 1, 1974·The Journal of Experimental Medicine·D E MosierP R McMaster

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