PMID: 4286616May 20, 1966Paper

Murine leukemia viruses: antigenic studies by quantitative complement fixation

Science
P GerberS M Birch

Abstract

The murine leukemia viruses of Rauscher and Friend, derived from plasnma of infected Balb/c mice, was purified. Their antigenic relationship was studied by quantitative complement-fixation reactions with the virion antigen and homologous antiserums. The complement-fixation curves observed in cross-reactions indicated close antigenic similarity between these two leukemia viruses. Highly purified viral preparations contained detectable amounts of host antigens.

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