PMID: 2497227May 1, 1989Paper

Murine V kappa gene expression does not follow the VH paradigm

The Journal of Experimental Medicine
A KaushikG Kelsoe

Abstract

V kappa gene family expression among LPS-reactive murine B lymphocytes, unlike that of VH gene families, is not proportional to genomic complexity, i.e., nonstoichiometric. Furthermore, no positional bias for the overexpression of J-proximal V kappa genes (V kappa 21) is observed among neonatal B lymphocytes. Yet, the V kappa 1 and V kappa 9 families located in the center of V kappa locus are preferentially used by neonatal B splenocytes. Thus, the mechanisms of V kappa gene rearrangement and expression appear to differ significantly from those controlling the VH locus.

References

Oct 1, 1988·European Journal of Immunology·L ReiningerJ C Jaton
Jul 1, 1988·The Journal of Experimental Medicine·G D YancopoulosF W Alt
Nov 20, 1987·Science·F W AltG D Yancopoulos
Mar 29, 1985·Science·R M PerlmutterL E Hood

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Citations

Sep 1, 1990·Journal of Clinical Immunology·C A BonaG Kelsoe
Sep 21, 2004·Immunogenetics·Katherine M Brekke, William T Garrard
Aug 1, 1993·Molecular Immunology·K N KasturiC A Bona
Aug 6, 2002·Seminars in Immunology·Yoram LouzounMartin Weigert
Sep 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·A M LawlerP J Gearhart
Jul 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·A KaushikG Kelsoe
Aug 1, 1990·The Journal of Experimental Medicine·S L Kalled, P H Brodeur
Feb 1, 1991·The Journal of Experimental Medicine·K Harada, H Yamagishi
Jan 1, 1990·International Reviews of Immunology·J L Hillson, R M Perlmutter
Jan 1, 1992·International Reviews of Immunology·A CoutinhoA Grandien
Jan 1, 1992·International Reviews of Immunology·C A Bona
Aug 1, 1989·Immunological Reviews·C Victor-KobrinC Bona
Jan 5, 2002·Immunity·H LiM Weigert
Aug 7, 2007·Molecular Immunology·P RichlH J Girschick
Jan 1, 1994·International Reviews of Immunology·K N KasturiC A Bona
Sep 1, 1995·European Journal of Immunology·P BoudinotP Sanchez
Feb 1, 1995·European Journal of Immunology·A KaushikJ C Jaton
Apr 1, 1991·European Journal of Immunology·P SanchezP A Cazenave
Jan 31, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Miyo Aoki-OtaDavid Nemazee
Jan 1, 1992·International Reviews of Immunology·J M Teale, C A Medina

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