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Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

bioRxiv

Jun 12, 2014

Yarden KatzChristopher B Burge

Abstract

Summary The conserved Musashi (Msi) family of RNA binding proteins are expressed in stem/progenitor and cancer cells, but mostly absent from differentiated cells, consistent with a role in cell state regulation. We found that Msi genes are rarely mutated but frequently overexpressed in ...read more

Mentioned in this Paper

In Vivo
Conserved Sequence
Msi1h protein, mouse
Patterns
Gene Knockdown Techniques
Post-Transcriptional Regulation
Genes
Mammary Gland
Jag1
Transcription, Genetic
14
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Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

bioRxiv

Jun 12, 2014

Yarden KatzChristopher B Burge

PMID: 990006270

DOI: 10.1101/006270

Abstract

Summary The conserved Musashi (Msi) family of RNA binding proteins are expressed in stem/progenitor and cancer cells, but mostly absent from differentiated cells, consistent with a role in cell state regulation. We found that Msi genes are rarely mutated but frequently overexpressed in ...read more

Mentioned in this Paper

In Vivo
Conserved Sequence
Msi1h protein, mouse
Patterns
Gene Knockdown Techniques
Post-Transcriptional Regulation
Genes
Mammary Gland
Jag1
Transcription, Genetic
14

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