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Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

bioRxiv

Jun 12, 2014

Yarden KatzChristopher B. Burge

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Abstract

The conserved Musashi (Msi) family of RNA binding proteins are expressed in stem/progenitor and cancer cells, but mostly absent from differentiated cells, consistent with a role in cell state regulation. We found that Msi genes are rarely mutated but frequently overexpressed in human ca...read more

Mentioned in this Paper

MSI1 gene
Gene Expression
Msi1h protein, mouse
Musashi protein, Drosophila
Regulation of Translation
Breast Cancer Cell
Tumor Cells, Malignant
Gene Knockdown Techniques
Ribosomes
Post-Transcriptional Regulation
14
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  • Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

    bioRxiv

    Jun 12, 2014

    Yarden KatzChristopher B. Burge

    PMID: 990006270

    DOI: 10.1101/006270

    Abstract

    The conserved Musashi (Msi) family of RNA binding proteins are expressed in stem/progenitor and cancer cells, but mostly absent from differentiated cells, consistent with a role in cell state regulation. We found that Msi genes are rarely mutated but frequently overexpressed in human ca...read more

    Mentioned in this Paper

    MSI1 gene
    Gene Expression
    Msi1h protein, mouse
    Musashi protein, Drosophila
    Regulation of Translation
    14

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