PMID: 8960976Oct 1, 1996Paper

Muscarinic and purinergic Ca2+ mobilizations in the neural retina of early embryonic chick

International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience
Y SakakiM Yamashita

Abstract

Acetylcholine and adenosine triphosphate (ATP) raise intracellular Ca2+ concentration via muscarinic receptors and P2U purinoceptors by releasing Ca2+ from intracellular Ca2+ stores in the neural retina of early embryonic chick. The signal transduction mechanisms for the muscarinic and purinergic Ca2+ responses were studied with fura-2 fluorescence measurements. Li+ (1 mM), which inhibits phosphatidylinositol metabolism, enhanced both the Ca2+ rises to carbamylcholine (CCh. 30 microM) a muscarinic agonist and ATP (200 microM). Thapsigargin (250 nM), an inhibitor of Ca(2+)-ATPase of inositol trisphosphate (IP3)-sensitive Ca2+ stores, abolished both the Ca2+ rises to CCh (100 microM) and ATP (500 microM). U-73122 (2 microM), an inhibitor of phospholipase C beta, suppressed the Ca2+ rise to ATP (500 microM), but its analog U-73343 (2 microM) did not suppress it. In contrast, both U-73122 and U-73343 suppressed the Ca2+ the Ca2+ rise to CCh (100 microM). Pertussis toxin (250 ng/ml) suppressed the ATP-induced Ca2+ rise at least partly, whereas no inhibition was observed on the CCh-induced Ca2+ rise. Cross-talk occurred between the muscarinic and purinergic Ca2+ mobilizations but they were not occlusive. This study suggests that the ...Continue Reading

References

Jan 1, 1990·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·T Laasberg
Jan 1, 1987·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·T LaasbergT Neuman
Apr 1, 1995·Trends in Pharmacological Sciences·M R BoarderG F Wilkinson
Sep 1, 1994·Journal of Neurobiology·M YamashitaY Fukuda
Oct 1, 1993·Endocrine Reviews·J W Putney, G S Bird
Dec 1, 1993·Journal of Neurobiology·M Yamashita, Y Fukuda
Sep 1, 1995·Journal of Neurobiology·Y Nakaoka, M Yamashita
Jun 15, 1996·The Journal of Physiology·M SugiokaM Yamashita
Jan 1, 1951·Journal of Morphology·V HAMBURGER, H L HAMILTON
Jan 1, 1984·Wilhelm Roux's Archives of Developmental Biology·Heinrich SchmidtUlrich Drews

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Citations

Apr 14, 2011·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M GrübJ M Rohrbach
Apr 12, 2008·Purinergic Signalling·Jesús PintorAssumpta Peral
Jul 12, 2003·Brain Research. Developmental Brain Research·Hidenori NaruokaTakehiko Saito
Oct 2, 2003·Brain Research. Developmental Brain Research·Motoko Ohmasa, Takehiko Saito
Mar 27, 2003·Neuroscience Research·Miho Sugioka, Masayuki Yamashita
May 15, 2002·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Glauco SanchesAna Lucia Marques Ventura
Aug 19, 1999·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M SugiokaM Yamashita
Aug 17, 2000·Biosensors & Bioelectronics·S M O'ConnorD A Stenger
Jul 10, 1999·Archives of Histology and Cytology·K KimuraY Satoh
Jan 12, 2011·Cellular and Molecular Life Sciences : CMLS·Geoffrey Burnstock, Henning Ulrich
Jun 15, 2010·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Isis Moraes Ornelas, Ana Lucia Marques Ventura
Oct 6, 2009·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Alfred Sholl-FrancoAna Lucia Marques Ventura
Oct 24, 2007·Journal of Pharmacological Sciences·Dae-Ran KimIn Deok Kong
Aug 1, 2012·Stem Cells International·Masayuki Yamashita
Aug 12, 1998·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·G Sanches, A L Ventura
Sep 7, 2006·Current Opinion in Allergy and Clinical Immunology·Amalia Enríquez-de-Salamanca, Margarita Calonge
Feb 19, 1998·Journal of Neurobiology·M SugiokaM Yamashita
Dec 10, 1999·Journal of Neurobiology·W L ZhouM Yamashita
Jun 16, 2007·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Guilherme Rapozeiro FrançaAna Lucia Marques Ventura
Nov 6, 2007·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Patricia Helena Castro NunesAna Lucia Marques Ventura
Apr 13, 1999·The American Journal of Physiology·S KhareT A Brasitus
Aug 16, 2000·American Journal of Physiology. Cell Physiology·B MoralesM Villalón
Jun 8, 2001·News in Physiological Sciences : an International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society·Masayuki Yamashita, Miho Sugioka
Feb 15, 2008·Neurochemical Research·Ricardo Augusto de Melo ReisFernando Garcia de Mello
Jun 29, 2007·Brain Research·Rodrigo A P Martins, Rachael A Pearson

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