Muscle changes in protein-deprived young rats. A morphometrical, histochemical and ultrastructural study

Journal of the Neurological Sciences
A OldforsP Sourander

Abstract

Rats were reared on a standard diet up to the age of 6 weeks when they were divided into two groups. One was fed on a diet containing 14% protein and the other on a diet with only 1.5% protein. The size of the various fibre types of the EDL muscle of both groups was assessed at 6 and 25 weeks of age. All the fibre types of protein-deprived rats were smaller compared to the age-matched controls, the difference being most evident in the 2B fibres. In the protein-deprived rats the 2B fibres atrophied while the type 1 and type 2A fibres simply failed to grow. Histochemical and ultrastructural examination revealed a marked reduction of the subsarcolemmal mitochondria after prolonged protein deprivation; normally large accumulations of mitochondria are seen preferentially in type 2A fibres.

References

May 1, 1979·The Proceedings of the Nutrition Society·D J Millward
Mar 1, 1979·The British Journal of Nutrition·F M Hansen-SmithM H Golden
Jul 1, 1965·The Journal of Pathology and Bacteriology·S ChauhanV Ramalingaswami
Mar 1, 1968·The Journal of Experimental Zoology·R W Rowe
Aug 1, 1981·Clinical Physiology·B EssénB Saltin
Nov 1, 1960·Stain Technology·K C RICHARDSONE H FINKE
Mar 1, 1961·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M S BURSTONE
Nov 1, 1962·Journal of Clinical Pathology·R D Montgomery

❮ Previous
Next ❯

Citations

May 1, 1985·Journal of the Neurological Sciences·A Oldfors, P Sourander
Sep 1, 1986·Journal of the Neurological Sciences·A Oldfors, P Sourander
Nov 1, 1991·Journal of the Neurological Sciences·M Ullman, A Oldfors
Jul 1, 1992·Journal of the Neurological Sciences·J S Chopra, A Sharma
Jan 1, 1988·Experimental Gerontology·R M Ludatscher, M Silbermann
Nov 1, 1994·Alcohol·J C RomeroN Batista
May 17, 2008·Avian Pathology : Journal of the W.V.P.A·M HaraguchiM L Dagli
Aug 31, 2004·Thorax·B PollaC Reggiani
Sep 1, 1989·American Journal of Respiratory Cell and Molecular Biology·P G WilcoxR L Pardy
Feb 20, 2010·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Bettina HesseNadja Schilling
Dec 1, 1990·Arquivos de neuro-psiquiatria·O J NascimentoM R Freitas
Jan 1, 1989·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·A OldforsI Fogdestam

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.