Muscle fiber atrophy in the quadriceps in knee-joint disorders. Histochemical studies on 112 cases

Archives of Orthopaedic and Trauma Surgery
T NakamuraH Miyashita

Abstract

In order to determine whether there is a different susceptibility of muscle fiber types in the m. vastus lateralis (VL) in knee-joint disorders, histochemical studies were performed on 112 cases. Anterior cruciate ligament (ACL) injuries affected 51 patients; ACL injuries associated with meniscus (ACL + M) injuries affected 29. Twenty-five patients had sustained meniscus injuries and seven had injuries of the collateral ligaments (CL). Fifty-two were athletic and 60 were not. On each biopsy, fiber-type distribution was obtained and the degree of atrophy of each fiber type was estimated from two parameters, the mean diameter and the percentage of atrophied fibers. The distribution of type-1 fibers averaged 38.0% +/- 12.0%. There were no significant differences among disorders in the distribution of type-1 fibers. Both parameters of fiber atrophy revealed a difference in susceptibility between type-1 and type-2 fibers. Atrophy of type-1 fibers was found only in ACL and ACL + M injuries. Type-2 fibers were atrophied in all four disorders. Atrophy of type-2 fibers could be a nonspecific change due to the inactivity of the VL, but type-1 fiber atrophy may relate specifically to the condition of ACL insufficiency.

References

Jan 1, 1980·Journal of the Neurological Sciences·A Sĭrca, M Susec-Michieli
Jan 1, 1984·The American Journal of Sports Medicine·S W ArmsE Eriksson
May 1, 1984·The American Journal of Sports Medicine·W H BaugherA Joseph
Nov 1, 1982·The American Journal of Sports Medicine·J C KennedyK C Hayes
Oct 1, 1953·The Journal of Physiology·I A BOYD, T D ROBERTS
Jul 1, 1960·Physiological Reviews·C C HUNT, E R PERL
May 1, 1948·The Anatomical Record·E GARDNER

❮ Previous
Next ❯

Citations

Aug 19, 2006·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·L HolmM Kjaer
Sep 29, 2006·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Helena GapeyevaMati Pääsuke
Dec 25, 2007·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Hisatada HiraokaHiroya Sakai
Mar 27, 2015·American Journal of Physiology. Cell Physiology·Damien M CallahanMichael J Toth
Feb 2, 2018·Medicine and Science in Sports and Exercise·Birgit Friedmann-BetteAlexander Barié

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Family Physician
Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA
Grethe Myklebust, Kathrin Steffen
Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA
Ejnar Eriksson
The American Journal of Sports Medicine
Bruce Reider
© 2021 Meta ULC. All rights reserved