Muscle mass and bone mineral indices: does the normalized bone mineral content differ with age?

European Journal of Clinical Nutrition
Kiyoshi SanadaM Higuchi

Abstract

To investigate the relationships between regional skeletal muscle mass (SM mass) and bone mineral indices and to examine whether bone mineral content (BMC) normalized to SM mass shows a similar decrease with age in young through old age. One hundred and thirty-eight young and postmenopausal women aged 20-76 years participated in this study and were divided into three groups: 61 young women, 49 middle-aged postmenopausal women and 28 older postmenopausal women. Muscle thickness (MTH) was determined by ultrasound, and regional SM mass (arm, trunk and leg) was estimated based on nine sites of MTH. Whole-body and regional lean soft tissue mass (LSTM), bone mineral density (BMD) and BMC (whole body, arms, legs and lumbar spine) were measured using dual-energy X-ray absorptiometry. Ultrasound spectroscopy indicated that SM mass is significantly correlated with site-matched regional bone mineral indices and these relationships correspond to LSTM. The BMC and BMD in older women were significantly lower than those in middle-aged women. When BMC was normalized to site-matched regional SM mass, BMC normalized to SM mass in arm and trunk region were significantly different with age; however, whole-body and leg BMC normalized to SM mass sho...Continue Reading

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Citations

Sep 23, 2014·Geriatrics & Gerontology International·Ryoko KawakamiMotohiko Miyachi
Sep 2, 2014·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Noriko I TanakaMotohiko Miyachi
Dec 24, 2014·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Selma Coelho LiberatoJosefina Bressan
Jan 7, 2015·Physiology·Susan A NovotnyMark W Hamrick

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